NDLI: Numerical Simulation of Magnetic Resonance Angiographies of an Anatomically Realistic Stenotic Carotid Bifurcation

Content Provider	Springer Nature Link
Author	Lorthois, Sylvie Stroud Rossman, Jenn Berger, Stanley Jou, Liang Der Saloner, David
Copyright Year	2005
Abstract	Magnetic Resonance Angiography (MRA) has become a routine imaging modality for the clinical evaluation of obstructive vascular disease. However, complex circulatory flow patterns, which redistribute the Magnetic Resonance (MR) signal in a complicated way, may generate flow artifacts and impair image quality. Numerical simulation of MRAs is a useful tool to study the mechanisms of artifactual signal production. The present study proposes a new approach to perform such simulations, applicable to complex anatomically realistic vascular geometries. Both the Navier-Stokes and the Bloch equations are solved on the same mesh to obtain the distribution of modulus and phase of the magnetization. The simulated angiography is subsequently constructed by a simple geometric procedure mapping the physical plane into the MRA image plane. Steady bidimensional numerical simulations of MRAs of an anatomically realistic severely stenotic carotid artery bifurcation are presented, for both time-of-flight and contrast-enhanced imaging modalities. These simulations are validated by qualitative comparison with flow phantom experiments performed under comparable conditions.
Starting Page	270
Ending Page	283
Page Count	14
File Format	PDF
ISSN	00906964
Journal	Annals of Biomedical Engineering
Volume Number	33
Issue Number	3
e-ISSN	15739686
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2005-01-01
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Magnetic resonance Angiography Bloch equations Computer simulation Flow artifacts Carotid stenoses Biochemistry Mechanics Biophysics/Biomedical Physics Vibration, Dynamical Systems, Control Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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