NDLI: Modeling Plaque Fissuring and Dissection during Balloon Angioplasty Intervention

Content Provider	Springer Nature Link
Author	Gasser, T. Christian Holzapfel, Gerhard A.
Copyright Year	2007
Abstract	Balloon angioplasty intervention is traumatic to arterial tissue. Fracture mechanisms such as plaque fissuring and/or dissection occur and constitute major contributions to the lumen enlargement. However, these types of mechanically-based traumatization of arterial tissue are also contributing factors to both acute procedural complications and chronic restenosis of the treatment site. We propose physical and finite element models, which are generally useable to trace fissuring and/or dissection in atherosclerotic plaques during balloon angioplasty interventions. The arterial wall is described as an anisotropic, heterogeneous, highly deformable, nearly incompressible body, whereas tissue failure is captured by a strong discontinuity kinematics and a novel cohesive zone model. The numerical implementation is based on the partition of unity finite element method and the interface element method. The later is used to link together meshes of the different tissue components. The balloon angioplasty-based failure mechanisms are numerically studied in 3D by means of an atherosclerotic-prone human external iliac artery, with a type V lesion. Image-based 3D geometry is generated and tissue-specific material properties are considered. Numerical results show that in a primary phase the plaque fissures at both shoulders of the fibrous cap and stops at the lamina elastica interna. In a secondary phase, local dissections between the intima and the media develop at the fibrous cap location with the smallest thickness. The predicted results indicate that plaque fissuring and dissection cause localized mechanical trauma, but prevent the main portion of the stenosis from high stress, and hence from continuous tissue damage.
Starting Page	711
Ending Page	723
Page Count	13
File Format	PDF
ISSN	00906964
Journal	Annals of Biomedical Engineering
Volume Number	35
Issue Number	5
e-ISSN	15739686
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2007-03-24
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Artery Atherosclerotic plaque Balloon angioplasty Cohesive zone model Dissection FEM Plaque fissuring Biochemistry Mechanics Biophysics/Biomedical Physics Biomedical Engineering Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Numerical simulation of arterial dissection during balloon angioplasty of atherosclerotic coronary arteries

Numerical simulation of arterial dissection during balloon angioplasty of atherosclerotic coronary arteries

Modeling of Experimental Atherosclerotic Plaque Delamination

In Vitro Angioplasty of Atherosclerotic Human Femoral Arteries: Analysis of the Geometrical Changes in the Individual Tissues Using MRI and Image Processing

A Numerical Model to Study the Interaction of Vascular Stents with Human Atherosclerotic Lesions

Biomechanics of Atherosclerotic Coronary Plaque: Site, Stability and In Vivo Elasticity Modeling

Modelling of Atherosclerotic Plaque for Use in a Computational Test-Bed for Stent Angioplasty

A hypothesis regarding vascular acoustic emission accompanying arterial injury induced by balloon angioplasty

Inelasticity of Human Carotid Atherosclerotic Plaque

Modeling Plaque Fissuring and Dissection during Balloon Angioplasty Intervention

Similar Documents

Numerical simulation of arterial dissection during balloon angioplasty of atherosclerotic coronary arteries

Numerical simulation of arterial dissection during balloon angioplasty of atherosclerotic coronary arteries

Modeling of Experimental Atherosclerotic Plaque Delamination

In Vitro Angioplasty of Atherosclerotic Human Femoral Arteries: Analysis of the Geometrical Changes in the Individual Tissues Using MRI and Image Processing

A Numerical Model to Study the Interaction of Vascular Stents with Human Atherosclerotic Lesions

Biomechanics of Atherosclerotic Coronary Plaque: Site, Stability and In Vivo Elasticity Modeling

Modelling of Atherosclerotic Plaque for Use in a Computational Test-Bed for Stent Angioplasty

A hypothesis regarding vascular acoustic emission accompanying arterial injury induced by balloon angioplasty

Inelasticity of Human Carotid Atherosclerotic Plaque

Modeling Plaque Fissuring and Dissection during Balloon Angioplasty Intervention