NDLI: Controlled counter-flow motion of magnetic bead chains rolling along microchannels

Content Provider	Springer Nature Link
Author	Karle, Marc Wöhrle, Johannes Miwa, Junichi Paust, Nils Roth, Günter Zengerle, Roland Stetten, Felix
Copyright Year	2010
Abstract	We demonstrate controlled transport of superparamagnetic beads in the opposite direction of a laminar flow. A permanent magnet assembles 200 nm magnetic particles into about 200 μm long bead chains that are aligned in parallel to the magnetic field lines. Due to a magnetic field gradient, the bead chains are attracted towards the wall of a microfluidic channel. A rotation of the permanent magnet results in a rotation of the bead chains in the opposite direction to the magnet. Due to friction on the surface, the bead chains roll along the channel wall, even in counter-flow direction, up to at a maximum counter-flow velocity of 8 mm s−1. Based on this approach, magnetic beads can be accurately manoeuvred within microfluidic channels. This counter-flow motion can be efficiently be used in Lab-on-a-Chip systems, e.g. for implementing washing steps in DNA purification.
Starting Page	935
Ending Page	939
Page Count	5
File Format	PDF
ISSN	16134982
Journal	Microfluidics and Nanofluidics
Volume Number	10
Issue Number	4
e-ISSN	16134990
Language	English
Publisher	Springer-Verlag
Publisher Date	2010-11-10
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Magnetic beads Lab-on-a-chip Transport Handling Engineering Fluid Dynamics Biomedical Engineering Industrial Chemistry/Chemical Engineering
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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