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| Content Provider | Springer Nature Link |
|---|---|
| Author | Huh, Yun Suk Chung, Aram J. Erickson, David |
| Copyright Year | 2008 |
| Abstract | In this paper, we review the state-of-the-art in surface-enhanced Raman scattering (SERS) based optical detection techniques with an application focus on cancer diagnostics. As we describe herein, SERS has several analytical, biological and engineering advantages over other methods including extremely high sensitivity, inherent molecular specificity of unlabeled targets, and narrow spectral bands. We review advances in both in vitro and in vivo applications of SERS and examine how technical issues with the technology are being addressed. A special technology focus is given to emerging optofluidic devices which aim to merge microfluidic and optical detection technologies into simple packages. We conclude with a brief discussion of some of the emerging challenges in the field and some of the approaches that are likely to enhance their application. |
| Starting Page | 285 |
| Ending Page | 297 |
| Page Count | 13 |
| File Format | |
| ISSN | 16134982 |
| Journal | Microfluidics and Nanofluidics |
| Volume Number | 6 |
| Issue Number | 3 |
| e-ISSN | 16134990 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2009-01-08 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Optical biosensors Surface enhanced Raman scattering SERS Cancer Optofluidics Tip-enhanced Raman spectroscopy Biomedical Engineering Engineering Fluid Dynamics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials |
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