NDLI: Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation

Please wait, while we are loading the content...

Marine Biotechnology : Volume 18

Marine Biotechnology : Volume 17

Marine Biotechnology : Volume 16

Marine Biotechnology : Volume 15

Marine Biotechnology : Volume 14

Marine Biotechnology : Volume 14, Issue 6, December 2012

Marine Biotechnology : Volume 14, Issue 5, October 2012

Marine Biotechnology : Volume 14, Issue 4, August 2012

Marine Biotechnology : Volume 14, Issue 3, June 2012

Marine Biotechnology : Volume 14, Issue 2, April 2012

Marine Biotechnology : Volume 14, Issue 1, February 2012

Development and Linkage Analysis of 104 New Microsatellite Markers for Bay Scallop (Argopecten irradians)

D-Xylose Isomerase from a Marine Bacterium, Vibrio sp. Strain XY-214, and d-Xylulose Production from β-1,3-Xylan

Multigene Barcoding and Phylogeny of Geographically Widespread Muricids (Gastropoda: Neogastropoda) Along the Coast of China

Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation

Hepatocyte Nuclear Factor 4α Transactivates the Mitochondrial Alanine Aminotransferase Gene in the Kidney of Sparus aurata

Protection of Shrimp against White Spot Syndrome Virus (WSSV) with β-1,3-d-glucan-encapsulated vp28-siRNA Particles

Transcriptomic Analysis of the Clam Meretrix meretrix on Different Larval Stages

Construction of an Integrated Map of Haliotis diversicolor Using Microsatellite Markers

An Extracellular S1-Type Nuclease of Marine Fungus Penicillium melinii

Distribution of Microfossils Within Polymetallic Nodules: Biogenic Clusters Within Manganese Layers

Role of Hypoxia-Inducible Factor α in Response to Hypoxia and Heat Shock in the Pacific Oyster Crassostrea gigas

Induction of Mitogynogenetic Diploids and Identification of WW Super-female Using Sex-Specific SSR Markers in Half-Smooth Tongue Sole (Cynoglossus semilaevis)

Marine Biotechnology : Volume 13

Marine Biotechnology : Volume 12

Marine Biotechnology : Volume 11

Marine Biotechnology : Volume 10

Marine Biotechnology : Volume 9

Marine Biotechnology : Volume 8

Marine Biotechnology : Volume 7

Marine Biotechnology : Volume 6

Marine Biotechnology : Volume 5

Marine Biotechnology : Volume 4

Marine Biotechnology : Volume 3

Marine Biotechnology : Volume 2

Marine Biotechnology : Volume 1

Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation

Content Provider	Springer Nature Link
Author	Tacchi, Luca Bickerdike, Ralph Secombes, Christopher J. Martin, Samuel A. M.
Copyright Year	2011
Abstract	The selection of proteins destined for degradation by the ubiquitin–proteasome pathway is coordinated by E3 ubiquitin ligases (E3Ub). One group of E3Ubs is described as muscle-specific RING finger (MuRF) molecules. In mammals, these proteins are believed to be central to targetting of muscle proteins for degradation during physiological perturbations such as starvation and inflammatory responses. In fish, the diversity of MuRF sequences is unexplored as is the expression of their mRNAs. In this study, three MuRF1 cDNAs, denoted as MuRF1a, MuRF1b, and MuRF1c, and a single MuRF2 were identified and characterized in Atlantic salmon. The MuRF1 sequences are highly conserved and encode predicted proteins of 349, 350, and 353 amino acids, whereas MuRF2 encodes a longer protein of 462 amino acids. The evolutionary relationship of these sequences with other fish and mammalian molecules shows that MuRF1a and 1b may have arisen from a recent salmonid duplication. The mRNA of MuRFs was expressed in multiple tissues, with highest abundance in white muscle tissue followed by the heart. The expression of MuRFs was modulated after both starvation and immune challenge. Starvation increased expression of all MuRF mRNAs in white muscle, with the greatest increase found in MuRF1a. A proinflammatory stimulation increased expression of MuRF mRNA in muscle and other tissues indicating a role of these proteins in protein degradation during inflammation.
Starting Page	35
Ending Page	45
Page Count	11
File Format	PDF
ISSN	14362228
Journal	Marine Biotechnology
Volume Number	14
Issue Number	1
e-ISSN	14362236
Language	English
Publisher	Springer-Verlag
Publisher Date	2011-05-17
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Atlantic salmon Proteasome MuRF1 MuRF2 Protein degradation E3 ubiquitin ligase Zoology Microbiology Engineering Freshwater & Marine Ecology
Content Type	Text
Resource Type	Article
Subject	Aquatic Science Biotechnology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

1staring, a novel e3 ubiquitin-protein ligase that targets syntaxin 1 for degradation.

Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes

High immune diversity in farmed Atlantic salmon (Salmo salar L.)

Early morphological predictors of maturity in one-sea-winter Atlantic salmon

HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation

Targeting the Ubiquitin E3 Ligase MuRF1 to Inhibit Muscle Atrophy

The use of hatchery technology for the conservation of Pacific and Atlantic salmon

Comparative Genomics Identifies Candidate Genes for Infectious Salmon Anemia (ISA) Resistance in Atlantic Salmon (Salmo salar)

Summer temperature variation and implications for juvenile Atlantic salmon

Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation

Similar Documents

1staring, a novel e3 ubiquitin-protein ligase that targets syntaxin 1 for degradation.

Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes

High immune diversity in farmed Atlantic salmon (Salmo salar L.)

Early morphological predictors of maturity in one-sea-winter Atlantic salmon

HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation

Targeting the Ubiquitin E3 Ligase MuRF1 to Inhibit Muscle Atrophy

The use of hatchery technology for the conservation of Pacific and Atlantic salmon

Comparative Genomics Identifies Candidate Genes for Infectious Salmon Anemia (ISA) Resistance in Atlantic Salmon (Salmo salar)

Summer temperature variation and implications for juvenile Atlantic salmon

Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation