NDLI: Pine needle extract suppresses adiposity via mediating adipogenic gene expressions of white adipose tissue in high fat diet-fed rats

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Pine needle extract suppresses adiposity via mediating adipogenic gene expressions of white adipose tissue in high fat diet-fed rats

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Pine needle extract suppresses adiposity via mediating adipogenic gene expressions of white adipose tissue in high fat diet-fed rats

Content Provider	Springer Nature Link
Author	Jeon, Jeong Ryae Choi, Joon Hyuk
Copyright Year	2013
Abstract	Effect of pine needle extract (PNE) on adiposity was examined through morphologic examination and adipogenic gene expression of white adipose tissue (WAT) in high fat diet (HFD)-fed rats. Four type diets; normal diet (ND), HFD, and diets respectively supplemented with PNE in both ND and HFD, were fed for 8 weeks. The adipose fat mass and the sizes in WAT were significantly lower in PNE-supplemented HFD group than in HFD group. The serum levels of PNE-supplemented HFD group were similar to those of ND group. The supplementation of PNE to HFD markedly increased adiponectin mRNA, but decreased those of leptin and tumor necrosis factor (TNF)-α in WAT, respectively. PNE enhanced glucose uptake of epididymal WAT under insulin stimulation. The results suggest that the beneficial effect of PNE supplementation on adipose fat and serum profiles in HFD-fed rats is partly modulated by adipogenic genes, such as adiponectin, leptin, and TNF-α mRNA in WAT.
Starting Page	465
Ending Page	470
Page Count	6
File Format	PDF
ISSN	12267708
Journal	Food Science and Biotechnology
Volume Number	22
Issue Number	2
e-ISSN	20926456
Language	English
Publisher	The Korean Society of Food Science and Technology
Publisher Date	2013-04-30
Publisher Place	Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	pine needle extract adiposity adiponectin leptin tumor necrosis factor-α Food Science Nutrition
Content Type	Text
Resource Type	Article
Subject	Applied Microbiology and Biotechnology Food Science Biotechnology

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