NDLI: Thermus thermophilus as biological model

Content Provider	Springer Nature Link
Author	Cava, Felipe Hidalgo, Aurelio Berenguer, José
Copyright Year	2009
Abstract	Thermus spp is one of the most wide spread genuses of thermophilic bacteria, with isolates found in natural as well as in man-made thermal environments. The high growth rates, cell yields of the cultures, and the constitutive expression of an impressively efficient natural competence apparatus, amongst other properties, make some strains of the genus excellent laboratory models to study the molecular basis of thermophilia. These properties, together with the fact that enzymes and protein complexes from extremophiles are easier to crystallize have led to the development of an ongoing structural biology program dedicated to T. thermophilus HB8, making this organism probably the best so far known from a protein structure point view. Furthermore, the availability of plasmids and up to four thermostable antibiotic selection markers allows its use in physiological studies as a model for ancient bacteria. Regarding biotechnological applications this genus continues to be a source of thermophilic enzymes of great biotechnological interest and, more recently, a tool for the over-expression of thermophilic enzymes or for the selection of thermostable mutants from mesophilic proteins by directed evolution. In this article, we review the properties of this organism as biological model and its biotechnological applications.
Starting Page	213
Ending Page	231
Page Count	19
File Format	PDF
ISSN	14310651
Journal	Extremophiles
Volume Number	13
Issue Number	2
e-ISSN	14334909
Language	English
Publisher	Springer Japan
Publisher Date	2009-01-21
Publisher Place	Japan
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Thermophiles Thermus Laboratory model Genetic tools Ecology Biotechnology Microbiology
Content Type	Text
Resource Type	Article
Subject	Medicine Molecular Medicine Microbiology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Identification of a replication initiation protein of the pVV8 plasmid from Thermus thermophilus HB8

Unique substrate specificity of purine nucleoside phosphorylases from Thermus thermophilus

Purification and characterization of a hyperthermostable Mn-superoxide dismutase from Thermus thermophilus HB27

Genome-wide comprehensive analysis of transcriptional regulation by ArgR in Thermus thermophilus

A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus

Phenylacetate Metabolism in Thermophiles: Characterization of Phenylacetate-CoA Ligase, the Initial Enzyme of the Hybrid Pathway in Thermus thermophilus

The third plasmid pVV8 from Thermus thermophilus HB8: isolation, characterization, and sequence determination

Mannosylglycerate is essential for osmotic adjustment in Thermus thermophilus strains HB27 and RQ-1

The DNA uptake ATPase PilF of Thermus thermophilus: a reexamination of the zinc content

Thermus thermophilus as biological model

Similar Documents

Identification of a replication initiation protein of the pVV8 plasmid from Thermus thermophilus HB8

Unique substrate specificity of purine nucleoside phosphorylases from Thermus thermophilus

Purification and characterization of a hyperthermostable Mn-superoxide dismutase from Thermus thermophilus HB27

Genome-wide comprehensive analysis of transcriptional regulation by ArgR in Thermus thermophilus

A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus

Phenylacetate Metabolism in Thermophiles: Characterization of Phenylacetate-CoA Ligase, the Initial Enzyme of the Hybrid Pathway in Thermus thermophilus

The third plasmid pVV8 from Thermus thermophilus HB8: isolation, characterization, and sequence determination

Mannosylglycerate is essential for osmotic adjustment in Thermus thermophilus strains HB27 and RQ-1

The DNA uptake ATPase PilF of Thermus thermophilus: a reexamination of the zinc content

Thermus thermophilus as biological model