NDLI: A gold electrode modified with amino-modified reduced graphene oxide, ion specific DNA and DNAzyme for dual electrochemical determination of Pb(II) and Hg(II)

Content Provider	Springer Nature Link
Author	Wang, Minghua Zhang, Shuai Ye, Zihan Peng, Donglai He, Linghao Yan, Fufeng Yang, Yanqin Zhang, Hongzhong Zhang, Zhihong
Copyright Year	2015
Abstract	Multilayered reduced graphene oxide (rGO) was functionalized with amino groups by treatment with nitrogen plasma. Raman spectroscopy showed plasma treatment not to substantially alter the chemical structure of rGO and that a wide range of functional nitrogen groups is evenly incorporated into the carbon lattice. The amino-modified rGO was used to design an electrochemical biosensor in which a DNAzyme, substrate DNA and Pb(II) and Hg(II) binding DNA were immobilized on the amino-rGO placed on a gold electrode. The high concentration of amino groups and the rough surface of the rGO favor DNA immobilization. Heavy metal ions are bound to the surface via specific interaction between DNA and the two ions which are detected by electrochemical impedance spectroscopy at a potential of 0.2 V (vs. Ag/AgCl). The detection limits for Pb(II) and Hg(II) are as low as 7.8 and 5.4 pM, respectively, and the analytical ranges extend from 0.01 to 100 nM. The sensor is highly specific and stable and therefore represents a highly promising tool for use in environmental monitoring. Graphical Abstract A nanofilm of reduced graphene oxide was first modified with amino groups by treatment with nitrogen plasma. A special DNA was then anchored to the surface to obtain a biosensor for simultaneous detection of Pb(II) and Hg(II). The sensor has detection limits as low as 7.8 and 5.4 pM and is highly selective.
Starting Page	2251
Ending Page	2258
Page Count	8
File Format	PDF
ISSN	00263672
Journal	Microchimica Acta
Volume Number	182
Issue Number	13-14
e-ISSN	14365073
Language	English
Publisher	Springer Vienna
Publisher Date	2015-07-22
Publisher Place	Vienna
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Plasma surface modification N2 plasma treatment Reduced graphene oxide Detection of Pb2+ Detection of Hg2+ Electrochemical biosensors Nanochemistry Nanotechnology Characterization and Evaluation of Materials Analytical Chemistry Microengineering
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Determination of melamine in food contact materials using an electrode modified with gold nanoparticles and reduced graphene oxide

Ultrasensitive electrochemical supersandwich DNA biosensor using a glassy carbon electrode modified with gold particle-decorated sheets of graphene oxide

Dopamine sensor based on a glassy carbon electrode modified with a reduced graphene oxide and palladium nanoparticles composite

Electrochemical aptasensor for lysozyme based on a gold electrode modified with a nanocomposite consisting of reduced graphene oxide, cuprous oxide, and plasma-polymerized propargylamine

Electrochemical sensors based on graphene materials

Electrochemical sensing of nitrite using a glassy carbon electrode modified with reduced functionalized graphene oxide decorated with flower-like zinc oxide

Impedance immunosensor for bovine interleukin-4 using an electrode modified with reduced graphene oxide and chitosan

Highly sensitive and selective voltammetric detection of mercury(II) using an ITO electrode modified with 5-methyl-2-thiouracil, graphene oxide and gold nanoparticles

Enzyme-based sensing of glucose using a glassy carbon electrode modified with a one-pot synthesized nanocomposite consisting of chitosan, reduced graphene oxide and gold nanoparticles

A gold electrode modified with amino-modified reduced graphene oxide, ion specific DNA and DNAzyme for dual electrochemical determination of Pb(II) and Hg(II)

Similar Documents

Determination of melamine in food contact materials using an electrode modified with gold nanoparticles and reduced graphene oxide

Ultrasensitive electrochemical supersandwich DNA biosensor using a glassy carbon electrode modified with gold particle-decorated sheets of graphene oxide

Dopamine sensor based on a glassy carbon electrode modified with a reduced graphene oxide and palladium nanoparticles composite

Electrochemical aptasensor for lysozyme based on a gold electrode modified with a nanocomposite consisting of reduced graphene oxide, cuprous oxide, and plasma-polymerized propargylamine

Electrochemical sensors based on graphene materials

Electrochemical sensing of nitrite using a glassy carbon electrode modified with reduced functionalized graphene oxide decorated with flower-like zinc oxide

Impedance immunosensor for bovine interleukin-4 using an electrode modified with reduced graphene oxide and chitosan

Highly sensitive and selective voltammetric detection of mercury(II) using an ITO electrode modified with 5-methyl-2-thiouracil, graphene oxide and gold nanoparticles

Enzyme-based sensing of glucose using a glassy carbon electrode modified with a one-pot synthesized nanocomposite consisting of chitosan, reduced graphene oxide and gold nanoparticles

A gold electrode modified with amino-modified reduced graphene oxide, ion specific DNA and DNAzyme for dual electrochemical determination of Pb(II) and Hg(II)