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| Content Provider | Springer Nature Link |
|---|---|
| Author | Saraiva, Ines Vande Wouwer, Alain Hantson, Anne Lise |
| Copyright Year | 2015 |
| Abstract | In this paper, we address the problem of parameter identification in dynamic models of animal cultures, and we propose a step-by-step procedure, which gradually considers more detailed models. This procedure allows subsets of parameters to be estimated at each step, which can be used in the initialization of the next identification step. Finally, the full parameter set can be re-estimated starting from the results of the last step. The efficiency of the procedure is illustrated with a simulation case study and with the identification of a dynamic model from experimental data collected in CHO cell culture. |
| Starting Page | 2231 |
| Ending Page | 2248 |
| Page Count | 18 |
| File Format | |
| ISSN | 16157591 |
| Journal | Bioprocess Engineering |
| Volume Number | 38 |
| Issue Number | 11 |
| e-ISSN | 16157605 |
| Language | English |
| Publisher | Springer Berlin Heidelberg |
| Publisher Date | 2015-09-03 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Mathematical modeling Parameter estimation Sensitivity analysis Animal cell cultures Biotechnology Industrial and Production Engineering Environmental Engineering/Biotechnology Industrial Chemistry/Chemical Engineering Food Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Bioengineering Biotechnology |
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