NDLI: Control strategies using diclazuril against coccidiosis in goat kids

Content Provider	Springer Nature Link
Author	Ruiz, Antonio Guedes, Aránzazu C. Muñoz, María C. Molina, José M. Hermosilla, Carlos Martín, Sergio Hernández, Yeray I. Hernández, Álvaro Pérez, Davinia Matos, Lorena López, Adassa M. Taubert, Anja
Copyright Year	2011
Abstract	Coccidiosis is probably the main parasitic disease affecting goat kids around the weaning period, leading to high economic losses in goat production due to deaths and delayed growth rates of infected animals. A total of 101 kids of 2–4 weeks of age, naturally infected with Eimeria spp., were divided into five groups and studies were conducted to analyse the effects of metaphylactic administration of diclazuril (Vecoxan®) on parasitological and productive parameters. Two different doses of diclazuril (1 and 2 mg/kg BW, p.o.) were given either at 3 weeks (single treatment) or at 3 and 5 weeks of life (double treatment). The faecal oocyst shedding and the body weights of the animals were monitored at 2-weeks intervals for 6 consecutive weeks. Treatments of goat kids with diclazuril were effective against the three most predominant Eimeria species recorded in this study (E. arloingi, E. ninakohlyakimovae and E. christenseni) and also against other minor species found in faecal examinations, including E. alijevi, E. caprina, E. jolchijevi, E. caprovina, E. hirci and E. aspheronica). In consequence, OPG values lower than 1 × 103 were detected in 90 to 100% of the animals up to 15–20 days post-treatment depending on the treatment regimen. Even a single dose of 1 mg/kg BW p.o. resulted in an increase of growth rates in treated animals and therefore should be considered as a control strategy in farms precluding coccidian infections, whilst double and multiple dose treatments could be the recommendation for environments heavily contaminated with Eimeria oocysts. In relation to the OPG reduction and increased growth rates, the severity of the clinical signs (i.e., diarrhoea) was ameliorated in treated animals during the course of infection compared to that of non-treated or control kids. The precise timing of treatment appears crucial in order to prevent severe clinical coccidiosis and thereby enabling the adequate development of protective immune response against Eimeria challenge infections.
Starting Page	2131
Ending Page	2136
Page Count	6
File Format	PDF
ISSN	09320113
Journal	Parasitology Research
Volume Number	110
Issue Number	6
e-ISSN	14321955
Language	English
Publisher	Springer-Verlag
Publisher Date	2011-12-23
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Medical Microbiology Immunology Microbiology
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Veterinary Parasitology Insect Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Study of the Comparative Efficacy of Toltrazuril and Diclazuril against Ovine Coccidiosis in Housed Lambs

Efficacy of nitazoxanide against experimental cryptosporidiosis in goat neonates

Control of Coccidiosis due to Eimeria bovis and Eimeria zuernii in Calves with Toltrazuril under Field Conditions in Comparison with Diclazuril and Untreated Controls

Porcine Coccidiosis – Investigations on the Cellular Immune Response against Isospora suis

Protective effect of Azadirachta indica extract against Eimeria papillata-induced coccidiosis

The DNA-induced protective immunity with chicken interferon gamma against poultry coccidiosis

Enteric coccidiosis in the brown kiwi (Apteryx mantelli)

The Epidemiology of Calf Coccidiosis (Eimeria spp.) in Poland

Studies on Coccidiosis of Calves in Hungarian Dairy Farms

Control strategies using diclazuril against coccidiosis in goat kids

Similar Documents

Study of the Comparative Efficacy of Toltrazuril and Diclazuril against Ovine Coccidiosis in Housed Lambs

Efficacy of nitazoxanide against experimental cryptosporidiosis in goat neonates

Control of Coccidiosis due to Eimeria bovis and Eimeria zuernii in Calves with Toltrazuril under Field Conditions in Comparison with Diclazuril and Untreated Controls

Porcine Coccidiosis – Investigations on the Cellular Immune Response against Isospora suis

Protective effect of Azadirachta indica extract against Eimeria papillata-induced coccidiosis

The DNA-induced protective immunity with chicken interferon gamma against poultry coccidiosis

Enteric coccidiosis in the brown kiwi (Apteryx mantelli)

The Epidemiology of Calf Coccidiosis (Eimeria spp.) in Poland

Studies on Coccidiosis of Calves in Hungarian Dairy Farms

Control strategies using diclazuril against coccidiosis in goat kids