NDLI: Expression of maf-B mRNA in the epithelium around the eyelid closure of the mouse eye at embryonic day 18

Content Provider	Springer Nature Link
Author	Kase, Satoru Imaki, Junko Harada, Takayuki Harada, Chikako Ohgami, Kazuhiro Shiratori, Kenji Sakai, Masaharu Nishi, Shinzo Oh, Shigeaki Yoshida, Kazuhiko
Copyright Year	2004
Abstract	Maf encodes a transcription factor protein containing a typical basic leucine zipper domain structure, a motif for protein dimerization and DNA binding. We examined the expression of maf-B mRNA in the epithelium around the eyelid closure. Expression of maf-B mRNA was examined in C57Bl6 mice at the embryonic stages in 12.5 days of gestation (E12.5) and E18 using in situ hybridization with 35S-labeled antisense riboprobes. In embryos studied 12.5 days postconception, a message specific for maf-B was not detected around the developing eyelid. In contrast, maf-B was strongly expressed in the epithelium of the eyelid closure at E18. Expression of maf-B was strongly noted in the suprabasal differentiating cells derived from the basal layer of the conjunctiva and epidermis. In contrast, basal cells in the eyelid closure and in the epidermis, as well as keratinizing cells, did not express maf-B. These data indicate that maf-B mRNA is expressed during development of the eyelid closure.
Starting Page	153
Ending Page	156
Page Count	4
File Format	PDF
ISSN	03402061
Journal	Anatomy and Embryology
Volume Number	209
Issue Number	2
e-ISSN	14320568
Language	English
Publisher	Springer-Verlag
Publisher Date	2004-11-19
Publisher Place	Berlin/Heidelberg
Access Restriction	Subscribed
Subject Keyword	E18 mouse Eyelid Maf-B
Content Type	Text
Resource Type	Article
Subject	Anatomy Cell Biology Developmental Biology Embryology

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