NDLI: Non-invasive assessment of carotid PWV via accelerometric sensors: validation of a new device and comparison with established techniques

Content Provider	Springer Nature Link
Author	Di Lascio, Nicole Bru, Rosa Maria Stea, Francesco Bianchini, Elisabetta Gemignani, Vincenzo Ghiadoni, Lorenzo Faita, Francesco
Copyright Year	2014
Abstract	Carotid pulse wave velocity (PWV) is considered as a surrogate marker for carotid stiffness and its assessment is increasingly being used in clinical practice. However, at the moment, its estimation needs specific equipment and a moderate level of technical expertise; moreover, it is based on a mathematical model. The aim of this study was to validate a new system for non-invasive and model-free carotid PWV assessment based on accelerometric sensors by comparison with currently used techniques.Accelerometric PWV (accPWV) values were obtained in 97 volunteers free of cardiovascular disease (age 24–85 years) and compared with standard ultrasound-based carotid stiffness parameters, such as carotid PWV (cPWV), relative distension (relD) and distensibility coefficient (DC). Moreover, the comparison between accPWV measurements and carotid-femoral PWV (cfPWV) was performed.Accelerometric PWV evaluations showed a significant correlation with cPWV measurements (R = 0.67), relD values (R = 0.66) and DC assessments (R = 0.64). These values were also significantly correlated with cfPWV evaluations (R = 0.46). In addition, the first attempt success rate was equal to 76.8 %.The accelerometric system allows a simple and quick local carotid stiffness evaluation and the values obtained with this system are significantly correlated with known carotid stiffness biomarkers. Therefore, the presented device could provide a concrete opportunity for an easy carotid stiffness evaluation even in clinical practice.
Starting Page	1503
Ending Page	1512
Page Count	10
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	114
Issue Number	7
e-ISSN	14396327
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2014-04-12
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Carotid stiffness Pulse wave velocity Accelerometric sensors Human Physiology Occupational Medicine/Industrial Medicine Sports Medicine
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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