| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Klassen, Stephen A. Dempster, Kylie S. Chirico, Daniele O’Leary, Deborah D. |
| Abstract | Purpose The present investigation evaluated the validity and reliability of carotidtoe PWV (ctPWV) as a non-intrusive measure of systemic arterial stiffness in healthy young adults. Methods The Validity Trial examined the association and agreement between cfPWV and ctPWV in 33 adults (24 ± 2 years; 14 females), while the Reliability Trial assessed the variability in cfPWV and ctPWV in 13 adults (22 ± 2 years; 5 females) over repeat visits. Proximal pulse waves were acquired (applanation tonometry) from the left common carotid (CCA) for both measures, while distal pulse waves were acquired from the left femoral artery (applanation tonometry) and the second left toe (pulse oximeter) for cfPWV and ctPWV, respectively. Results cfPWV (5.3 ± 0.7, 3.9–6.5 m/s) and ctPWV (5.4 ± 0.5, 4.6–6.3 m/s) demonstrated a moderate-to-strong positive linear correlation (r = 0.79, P < 0.01) and a strong intra-class correlation (ICC; ICC = 0.86, P < 0.01). The Bland—Altman plot demonstrated agreement between cfPWV and ctPWV with no fixed bias (0.1 m/s, ± 2SD: -0.8 to 0.9 m/s, P > 0.05) and all data points falling within ±2 SD of the mean difference between measures. cfPWV and ctPWV demonstrated reliability across visits as evidenced by low coefficients of variation (cfPWV: 3.4 ± 2.6%, ctPWV: 2.6 ± 2.5%) and strong ICCs (cfPWV: ICC = 0.91, ctPWV: ICC = 0.84, both P < 0.01). Conclusions Through comparison with cfPWV, this study provides evidence to suggest that ctPWV yields a valid and reliable index of arterial stiffness in healthy young adults. |
| Related Links | https://arteryresearch.biomedcentral.com/counter/pdf/10.1016/j.artres.2018.07.001.pdf |
| Ending Page | 38 |
| Page Count | 7 |
| Starting Page | 32 |
| File Format | HTM / HTML |
| ISSN | 18764401 |
| DOI | 10.1016/j.artres.2018.07.001 |
| Journal | Artery Research |
| Issue Number | 1 |
| Volume Number | 23 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2018-07-28 |
| Access Restriction | Open |
| Subject Keyword | Medicine Public Health Arterial stiffness Carotid-toe pulse wave velocity Carotid-femoral pulse wave velocity Validity Reliability Tonometry Medicine/Public Health |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology (medical) Physiology |
| Journal Impact Factor | 0.9/2023 |
| 5-Year Journal Impact Factor | 0.7/2023 |
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