NDLI: Aortic, cerebral and lower limb arterial and venous response to orthostatic stress after a 60-day bedrest

Content Provider	Springer Nature Link
Author	Arbeille, P. Shoemaker, K. Kerbeci, P. Schneider, S. Hargens, A. Hughson, R.
Copyright Year	2011
Abstract	The objective of this study is to assess by echography and Doppler the Cerebral (Vmca), Aortic (Vao) and Femoral (Vfem) arterial flow velocity and calf vein (Tibial, Gastrocnemius) section (Tib, Gast) during orthostatic intolerance (OI) test after a 60-day, head down tilt bed rest (HDBR). Twenty-four women (25–40 years) underwent a 60-day HDBR at −6°: eight as control (Con), eight with exercise against lower body negative pressure (Ex-Lb) and eight with nutrition supplement (Nut). Before and after (R0) HDBR, all subjects underwent a 10-min, 80° tilt followed by progressive LBNP until presyncope. After the post-HDBR Tilt + LBNP test, two groups were identified: finishers (F, n = 11) who completed the Tilt and non-finishers (NF, n = 13). A higher percentage decrease in Vao flow, higher percentage distension of Tib vein and a lack of increase in Vmca/Vfem ratio during the post-HDBR Tilt + LBNP compared to pre-HDBR were correlated to OI, but not all of these abnormal responses were present in each of the NF subjects. Abnormal responses were more frequent in Con and Nut than in Ex-Lb subjects. (1) HDBR did not affect the cardiac, arterial and venous responses to the orthostatic test to the same extent in each subject. (2) Exercise within LBNP partially preserved the cardiovascular response to Tilt, while Nutrition supplementation had no efficacy. (3) Cerebral/femoral flow ratio and aortic flow were the parameters most closely related to OI. (4) Reduction in aortic flow was not the major hemodynamic change preceding syncope.
Starting Page	277
Ending Page	284
Page Count	8
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	112
Issue Number	1
e-ISSN	14396327
Language	English
Publisher	Springer-Verlag
Publisher Date	2011-05-04
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Tilt LBNP Orthostatic tolerance Cerebral Aortic Femoral flow Occupational Medicine/Industrial Medicine Human Physiology Sports Medicine
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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Aortic, cerebral and lower limb arterial and venous response to orthostatic stress after a 60-day bedrest

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