NDLI: Different effects of PM10 exposure on preterm birth by gestational period estimated from time-dependent survival analyses

Content Provider	Springer Nature Link
Author	Suh, Young Ju Kim, Ho Seo, Ju Hee Park, Hyesook Kim, Young Ju Hong, Yun Chul Ha, Eun Hee
Copyright Year	2008
Abstract	We conducted this study to determine if the preterm risks due to PM10 exposure vary with the exposure periods during pregnancy. This study was also conducted to estimate the different effects of PM10 exposure on preterm birth by exposure periods using the extended Cox model with PM10 exposure as a time-dependent covariate.We studied birth data obtained from the Korea National Statistical office for 374,167 subjects who were delivered between 1998 and 2000 in Seoul, South Korea. We used PM10 data that was measured hourly to give 24-h averages at 27 monitoring stations in Seoul. The extended Cox model with time-dependent exposure was used to determine if the risk of preterm delivery could be associated with PM10 exposures for each trimester during pregnancy.Effect of PM10 exposure prior to the 37 weeks of gestational period was stronger on the risk of premature birth than that posterior to the 37 weeks of gestational weeks. This trend was consistent for each trimester; however, the hazard ratios for preterm delivery associated with PM10 exposure in the first and third trimester were slightly higher than those of the second trimester.The risk of preterm birth associated with exposure to PM10 differed with the exposure period of the neonates. Therefore, when studying the impact of air pollution exposure during pregnancy, the exposure period during pregnancy should be considered.
Starting Page	613
Ending Page	621
Page Count	9
File Format	PDF
ISSN	03400131
Journal	International Archives of Occupational and Environmental Health
Volume Number	82
Issue Number	5
e-ISSN	14321246
Language	English
Publisher	Springer-Verlag
Publisher Date	2008-11-08
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Preterm birth PM10 exposure Extended Cox model Environmental Health Rehabilitation Occupational Medicine/Industrial Medicine
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health

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