NDLI: Evidence for estrogen receptor α and β expression in skeletal muscle of pigs

Content Provider	Springer Nature Link
Author	Kalbe, Claudia Mau, Marcus Wollenhaupt, Karin Rehfeldt, Charlotte
Copyright Year	2006
Abstract	Recent research suggests that estrogen receptors (ERs) are of significance in skeletal muscle function. The aim of the present study was to investigate, whether ERα and ERβ are expressed in different porcine skeletal muscles and in satellite cells derived from semimembranosus muscle (SM) at the protein and mRNA level. Immunohistochemistry demonstrated positive staining for ERα in the nuclei of skeletal muscle cells, while the ERβ stain showed positive signals in nuclei and cytoplasm of skeletal myofibers and myoblasts derived from satellite cells. Additionally, a weak expression of both ER subtypes was seen in skeletal muscle tissue and SM satellite cells with Western blot analysis. A clear expression of the ERα mRNA and a weak expression of the ERβ mRNA was seen in skeletal muscle tissue and SM satellite cell cultures, as determined by reverse transcription (RT)-PCR. The present study shows for the first time that both ERα and ERβ are expressed in porcine skeletal muscle, which, consequently, could be considered as a target tissue for estrogens or estrogen-like compounds. However, more detailed studies on the functional impact of both receptor subtypes in skeletal muscle are necessary. The porcine SM satellite cell culture provides a suitable in vitro model to investigate estrogenic effects on pig skeletal muscle.
Starting Page	95
Ending Page	107
Page Count	13
File Format	PDF
ISSN	09486143
Journal	Histochemistry and Cell Biology
Volume Number	127
Issue Number	1
e-ISSN	1432119X
Language	English
Publisher	Springer-Verlag
Publisher Date	2006-08-03
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Pig Skeletal muscle Satellite cells Estrogen receptor Expression Medicine/Public Health Anatomy
Content Type	Text
Resource Type	Article
Subject	Cell Biology Histology Molecular Biology Medical Laboratory Technology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Effects of leptin and adiponectin on proliferation and protein metabolism of porcine myoblasts

Switching of actin isoforms in skeletal muscle differentiation using mouse ES cells

Expression pattern of estrogen receptors α and β and G-protein-coupled estrogen receptor 1 in the human testis

Potential sources of early-postnatal increase in myofibre number in pig skeletal muscle

Differentiation of activated satellite cells in denervated muscle following single fusions in situ and in cell culture

Estrogen-dependent regulation of sodium/hydrogen exchanger-3 (NHE3) expression via estrogen receptor β in proximal colon of pregnant mice

Gender- and region-specific variations of estrogen receptor α and β expression in the growth plate of spine and limb during development and adulthood

Oestrogen receptor β is present in both muscle fibres and endothelial cells within human skeletal muscle tissue

Functional properties of muscle-derived cells related to morphological characteristics

Evidence for estrogen receptor α and β expression in skeletal muscle of pigs

Similar Documents

Effects of leptin and adiponectin on proliferation and protein metabolism of porcine myoblasts

Switching of actin isoforms in skeletal muscle differentiation using mouse ES cells

Expression pattern of estrogen receptors α and β and G-protein-coupled estrogen receptor 1 in the human testis

Potential sources of early-postnatal increase in myofibre number in pig skeletal muscle

Differentiation of activated satellite cells in denervated muscle following single fusions in situ and in cell culture

Estrogen-dependent regulation of sodium/hydrogen exchanger-3 (NHE3) expression via estrogen receptor β in proximal colon of pregnant mice

Gender- and region-specific variations of estrogen receptor α and β expression in the growth plate of spine and limb during development and adulthood

Oestrogen receptor β is present in both muscle fibres and endothelial cells within human skeletal muscle tissue

Functional properties of muscle-derived cells related to morphological characteristics

Evidence for estrogen receptor α and β expression in skeletal muscle of pigs