NDLI: Plant sterol ester–enriched milk and yoghurt effectively reduce serum cholesterol in modestly hypercholesterolemic subjects

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Plant sterol ester–enriched milk and yoghurt effectively reduce serum cholesterol in modestly hypercholesterolemic subjects

Content Provider	Springer Nature Link
Author	akes, Manny Clifton, P. M. Doornbos, A. M. E. Trautwein, E. A.
Copyright Year	2004
Abstract	The cholesterol–lowering efficacy of plant sterol esters (PSteE) or stanol esters (PStaE) in regular– and low–fat spreads has been consistently demonstrated, while their effectiveness in a low–fat, aqueous food carrier such as milk and yoghurt is less well established.Two studies were carried out to assess the cholesterol–lowering effect of PSteE–enriched low-fat milk and PSteE– and PStaE–enriched low–fat yoghurt in modestly hypercholesterolemic subjects (total cholesterol between 5–7.5 mmol/l).Study one was a single blind crossover design with 4 phases of 3–week interventions. Subjects consumed 300ml/d of placebo or PSteE–milk (2.0 g plant sterols/d) alone or combined with 25 g/d of placebo or PSteE–spread. Study two was a fully randomised, double blind crossover design with 3 phases of 3–week interventions. Subjects consumed 2 portions (150 g tubs each) of placebo, PSteE–yoghurt (1.8 g plant sterols/d) or PStaE–yoghurt (1.7 g plant stanols/d). In study one 39 subjects (21 men and 18 women) and in study two 40 subjects (17 men and 23 women) completed the dietary intervention.In study one, PSteE–milk and PSteE–spread were equally efficacious in lowering total and LDL–cholesterol as compared to placebo by 6–8% and 8–10%, respectively. No significant additional cholesterol–lowering was observed with the combination of PSteE–milk and PSteE–spread (4 g plant sterols/d). PSteE–enriched milk and the combination of PSteE–enriched milk plus spread both lowered lipid–adjusted serum β–carotene concentrations by 10–14% (P < 0.02),while the PSteE–rich spread alone did not significantly alter serum β–carotene levels. In study two, the PSteE– and PStaE–enriched yoghurts reduced LDL–cholesterol significantly compared to placebo by 0.27 ± 0.05 mmol/l (6%) and 0.23 ± 0.05 mmol/l (5 %), respectively. In both studies, there was no effect on HDL–cholesterol and triacylglycerol concentrations.Plant sterols in the form of their esters when provided in lowfat milk and yoghurt are effective in lowering total and LDL–cholesterol.
Starting Page	214
Ending Page	222
Page Count	9
File Format	PDF
ISSN	14366207
Journal	European Journal of Nutrition
Volume Number	44
Issue Number	4
e-ISSN	14366215
Language	English
Publisher	Steinkopff-Verlag
Publisher Date	2004-08-17
Publisher Place	Darmstadt
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	modestly hypercholesterolemic subjects milk yoghurt plant sterols low–fat foods Nutrition
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

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