NDLI: Cloning, characterisation and regulation of the ornithine transaminase (otaA) gene of Aspergillus nidulans

Content Provider	Springer Nature Link
Author	Dzikowska, A. Swianiewicz, M. Talarczyk, A. Wisniewska, M. Goras, M. Scazzocchio, C. Weglenski, P.
Copyright Year	1999
Abstract	The ornithine transaminase (otaA) gene of Aspergillus nidulans has been cloned by transformation of the A. nidulans pro – ota – mutant strain with a cosmid gene library. The otaA gene contains two introns and potentially codes for a 453-aa-long protein. The deduced amino-acid sequence is homologous to known ornithine transaminases from Saccharomyces cerevisiae, Plasmodium falciparum, Vigna aconitifolia, rat, mouse and man, particularly in the pyridoxal phosphate-binding domain. The expression of the otaA gene is specifically induced by arginine, and is also under the control of nitrogen-metabolite and carbon-catabolite repression. Regulation of the gene occurs at both transcriptional and post-transcriptional levels. The promoter region of otaA contains putative AREA and CREA binding-sites. Fusion proteins containing AREA or CREA DNA-binding domains bind some of these sites. CREA binding-sites correspond very well to the CREA-binding consensus sequence which is SYGGRG. AREA binding-sites are composed of GATT sequences which are not typical binding sites for the GATA - binding family of transcription factors.
Starting Page	118
Ending Page	126
Page Count	9
File Format	PDF
ISSN	01728083
Journal	Current Genetics
Volume Number	35
Issue Number	2
e-ISSN	14320983
Language	English
Publisher	Springer-Verlag
Publisher Date	1999-03-09
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Genetics Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Cloning and characterisation of the adenosyl phosphosulphate kinase gene from Aspergillus nidulans

Cloning of a prolidase gene from Aspergillus nidulans and characterisation of its product

Isolation and characterisation of the acetyl-CoA carboxylase gene from Aspergillus nidulans

Cloning and characterization of the Aspergillus nidulans cysB gene encoding cysteine synthase

The metG gene of Aspergillus nidulans encoding cystathionine b-lyase: cloning and analysis

Regulation of the Aspergillus nidulans hisB gene by histidine starvation

Structure and regulation of cysD, the homocysteine synthase gene of Aspergillus nidulans

The veA gene is necessary for the negative regulation of the veA expression in Aspergillus nidulans

Isolation and characterisation of cycloheximide-sensitive mutants of Aspergillus nidulans

Cloning, characterisation and regulation of the ornithine transaminase (otaA) gene of Aspergillus nidulans

Similar Documents

Cloning and characterisation of the adenosyl phosphosulphate kinase gene from Aspergillus nidulans

Cloning of a prolidase gene from Aspergillus nidulans and characterisation of its product

Isolation and characterisation of the acetyl-CoA carboxylase gene from Aspergillus nidulans

Cloning and characterization of the Aspergillus nidulans cysB gene encoding cysteine synthase

The metG gene of Aspergillus nidulans encoding cystathionine b-lyase: cloning and analysis

Regulation of the Aspergillus nidulans hisB gene by histidine starvation

Structure and regulation of cysD, the homocysteine synthase gene of Aspergillus nidulans

The veA gene is necessary for the negative regulation of the veA expression in Aspergillus nidulans

Isolation and characterisation of cycloheximide-sensitive mutants of Aspergillus nidulans

Cloning, characterisation and regulation of the ornithine transaminase (otaA) gene of Aspergillus nidulans