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  1. Springer Seminars in Immunopathology
  2. Springer Seminars in Immunopathology : Volume 33
  3. Springer Seminars in Immunopathology : Volume 33, Issue 1, January 2011
  4. The pancreas in human type 1 diabetes
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Springer Seminars in Immunopathology : Volume 39
Springer Seminars in Immunopathology : Volume 38
Springer Seminars in Immunopathology : Volume 37
Springer Seminars in Immunopathology : Volume 36
Springer Seminars in Immunopathology : Volume 35
Springer Seminars in Immunopathology : Volume 34
Springer Seminars in Immunopathology : Volume 33
Springer Seminars in Immunopathology : Volume 33, Issue 6, November 2011
Springer Seminars in Immunopathology : Volume 33, Issue 5, September 2011
Springer Seminars in Immunopathology : Volume 33, Issue 4, July 2011
Springer Seminars in Immunopathology : Volume 33, Issue 3, May 2011
Springer Seminars in Immunopathology : Volume 33, Issue 2, March 2011
Springer Seminars in Immunopathology : Volume 33, Issue 1, January 2011
Beta cells under attack: toward a better understanding of type 1 diabetes immunopathology
Immunopathology of the human pancreas in type-I diabetes
Beta cell regeneration in human pancreas
The pancreas in human type 1 diabetes
Enteroviruses in the pathogenesis of type 1 diabetes
Innate immunity and the pathogenesis of type 1 diabetes
Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease
Springer Seminars in Immunopathology : Volume 32
Springer Seminars in Immunopathology : Volume 31
Springer Seminars in Immunopathology : Volume 30
Springer Seminars in Immunopathology : Volume 29
Springer Seminars in Immunopathology : Volume 28
Springer Seminars in Immunopathology : Volume 27
Springer Seminars in Immunopathology : Volume 26
Springer Seminars in Immunopathology : Volume 25
Springer Seminars in Immunopathology : Volume 24
Springer Seminars in Immunopathology : Volume 23
Springer Seminars in Immunopathology : Volume 22
Springer Seminars in Immunopathology : Volume 21
Springer Seminars in Immunopathology : Volume 20
Springer Seminars in Immunopathology : Volume 19
Springer Seminars in Immunopathology : Volume 18

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The pancreas in human type 1 diabetes

Content Provider Springer Nature Link
Author Rowe, Patrick A. Campbell Thompson, Martha L. Schatz, Desmond A. Atkinson, Mark A.
Copyright Year 2010
Abstract Type 1 diabetes (T1D) is considered a disorder whose pathogenesis is autoimmune in origin, a notion drawn in large part from studies of human pancreata performed as far back as the 1960s. While studies of the genetics, epidemiology, and peripheral immunity in T1D have been subject to widespread analysis over the ensuing decades, efforts to understand the disorder through analysis of human pancreata have been far more limited. We have reviewed the published literature pertaining to the pathology of the human pancreas throughout all stages in the natural history of T1D. This effort uncovered a series of findings that challenge many dogmas ascribed to T1D and revealed data suggesting the marked heterogeneity in terms of its pathology. An improved understanding and appreciation for pancreatic pathology in T1D could lead to improved disease classification, an understanding of why the disorder occurs, and better therapies for disease prevention and management.
Starting Page 29
Ending Page 43
Page Count 15
File Format PDF
ISSN 18632297
Journal Springer Seminars in Immunopathology
Volume Number 33
Issue Number 1
e-ISSN 18632300
Language English
Publisher Springer-Verlag
Publisher Date 2010-05-22
Publisher Place Berlin, Heidelberg
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Inflammation Insulin Islet cells Pancreas T-lymphocyte Type 1 diabetes Immunology Internal Medicine
Content Type Text
Resource Type Article
Subject Immunology and Allergy Immunology
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