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  1. Cellular and Molecular Life Sciences
  2. Cellular and Molecular Life Sciences : Volume 69
  3. Cellular and Molecular Life Sciences : Volume 69, Issue 24, December 2012
  4. Dynamics of ESCRT proteins
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Cellular and Molecular Life Sciences : Volume 73
Cellular and Molecular Life Sciences : Volume 72
Cellular and Molecular Life Sciences : Volume 71
Cellular and Molecular Life Sciences : Volume 70
Cellular and Molecular Life Sciences : Volume 69
Cellular and Molecular Life Sciences : Volume 69, Issue 24, December 2012
Poly(ADP-ribose) polymerase-2: emerging transcriptional roles of a DNA-repair protein
Are Rab proteins the link between Golgi organization and membrane trafficking?
Energy dysfunction in Huntington’s disease: insights from PGC-1α, AMPK, and CKB
Dynamics of ESCRT proteins
Regulated expression and neural functions of human natural killer-1 (HNK-1) carbohydrate
Knowledge translation: airway epithelial cell migration and respiratory diseases
Ca2+ release-activated Ca2+ (CRAC) current, structure, and function
The faah gene is the first direct target of estrogen in the testis: role of histone demethylase LSD1
Replacement of huntingtin exon 1 by trans-splicing
How broadly tuned olfactory receptors equally recognize their agonists. Human OR1G1 as a test case
NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity
Citrate kills tumor cells through activation of apical caspases
Erratum to: Identification of functional differences between recombinant human α and β cardiac myosin motors
Cellular and Molecular Life Sciences : Volume 69, Issue 23, December 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 21, November 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 22, November 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 20, October 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 19, October 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 17, September 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 18, September 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 15, August 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 16, August 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 13, July 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 14, July 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 12, June 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 11, June 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 10, May 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 9, May 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 7, April 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 8, April 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 5, March 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 6, March 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 4, February 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 3, February 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 2, January 2012
Cellular and Molecular Life Sciences : Volume 69, Issue 1, January 2012
Cellular and Molecular Life Sciences : Volume 68
Cellular and Molecular Life Sciences : Volume 67
Cellular and Molecular Life Sciences : Volume 66
Cellular and Molecular Life Sciences : Volume 65
Cellular and Molecular Life Sciences : Volume 64
Cellular and Molecular Life Sciences : Volume 63
Cellular and Molecular Life Sciences : Volume 62
Cellular and Molecular Life Sciences : Volume 61
Cellular and Molecular Life Sciences : Volume 60
Cellular and Molecular Life Sciences : Volume 59
Cellular and Molecular Life Sciences : Volume 58
Cellular and Molecular Life Sciences : Volume 57
Cellular and Molecular Life Sciences : Volume 56
Cellular and Molecular Life Sciences : Volume 55
Cellular and Molecular Life Sciences : Volume 54
Cellular and Molecular Life Sciences : Volume 53

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Dynamics of ESCRT proteins

Content Provider Springer Nature Link
Author Jouvenet, lwenn
Copyright Year 2012
Abstract Proteins of the ESCRT (endosomal sorting complex required for transport) complex function in membrane fission processes, such as multivesicular body (MVBs) formation, the terminal stages of cytokinesis, and separation of enveloped viruses from the plasma membrane. In mammalian cells, the machinery consists of a network of more than 20 proteins, organized into three complexes (ESCRT-I, -II, and -III), and other associated proteins such as the ATPase vacuolar protein sorting 4 (Vps4). Early biochemical studies of MVBs biogenesis in yeast support a model of sequential recruitment of ESCRT complexes on membranes. Live-cell imaging of ESCRT protein dynamics during viral budding and cytokinesis now reveal that this long-standing model of sequential assembly and disassembly holds true in mammalian cells.
Starting Page 4121
Ending Page 4133
Page Count 13
File Format PDF
ISSN 1420682X
Journal Cellular and Molecular Life Sciences
Volume Number 69
Issue Number 24
e-ISSN 14209071
Language English
Publisher SP Birkhäuser Verlag Basel
Publisher Date 2012-06-06
Publisher Place Basel
Access Restriction Subscribed
Subject Keyword ESCRT machinery Viral budding Cytokinesis Live cell imaging Cell Biology Biomedicine general Life Sciences Biochemistry
Content Type Text
Resource Type Article
Subject Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience
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