NDLI: Crosstalk between cerebral endothelium and oligodendrocyte

Content Provider	Springer Nature Link
Author	Miyamoto, bukazu Pham, Loc Duyen D. Seo, Ji Hae Kim, Kyu Won Lo, Eng H. Arai, Ken
Copyright Year	2013
Abstract	It is now relatively well accepted that the cerebrovascular system does not merely provide inert pipes for blood delivery to the brain. Cerebral endothelial cells may compose an embedded bunker of trophic factors that contribute to brain homeostasis and function. Recent findings suggest that soluble factors from cerebral endothelial cells nourish neighboring cells, such as neurons and astrocytes. Although data are strongest in supporting mechanisms of endothelial-neuron and/or endothelial-astrocyte trophic coupling, it is likely that similar interactions also exist between cerebral endothelial cells and oligodendrocyte lineage cells. In this mini-review, we summarize current advances in the field of endothelial-oligodendrocyte trophic coupling. These endothelial-oligodendrocyte interactions may comprise the oligovascular niche to maintain their cellular functions and sustain ongoing angiogenesis/oligodendrogenesis. Importantly, it should be noted that the cell–cell interactions are not static—the trophic coupling is disturbed under acute phase after brain injury, but would be recovered in the chronic phase to promote brain remodeling and repair. Oligodendrocyte lineage cells play critical roles in white matter function, and under pathological conditions, oligodendrocyte dysfunction lead to white matter damage. Therefore, a deeper understanding of the mechanisms of endothelial-oligodendrocyte trophic coupling may lead to new therapeutic approaches for white matter-related diseases, such as stroke or vascular dementia.
Starting Page	1055
Ending Page	1066
Page Count	12
File Format	PDF
ISSN	1420682X
Journal	Cellular and Molecular Life Sciences
Volume Number	71
Issue Number	6
e-ISSN	14209071
Language	English
Publisher	Springer Basel
Publisher Date	2013-10-17
Publisher Place	Basel
Access Restriction	Subscribed
Subject Keyword	Oligodendrocytes Oligodendrocyte precursor cells Cerebral endothelial cells Oligovascular niche Neurovascular unit Cell Biology Biomedicine general Life Sciences Biochemistry
Content Type	Text
Resource Type	Article
Subject	Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells

Crosstalk between cerebral endothelium and oligodendrocyte

Hypoxia in the regulation of neural stem cells

Inhibition of endogenous phosphodiesterase 7 promotes oligodendrocyte precursor differentiation and survival

Iron transport across the blood–brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy

Endothelial nitric oxide synthase in the microcirculation

Vascular growth factors in neuropsychiatry

Specification and function of hemogenic endothelium during embryogenesis

Crosstalk between cerebral endothelium and oligodendrocyte

Similar Documents

An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells

Crosstalk between cerebral endothelium and oligodendrocyte

Hypoxia in the regulation of neural stem cells

Inhibition of endogenous phosphodiesterase 7 promotes oligodendrocyte precursor differentiation and survival

Iron transport across the blood–brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy

Endothelial nitric oxide synthase in the microcirculation

Vascular growth factors in neuropsychiatry

Specification and function of hemogenic endothelium during embryogenesis

Crosstalk between cerebral endothelium and oligodendrocyte