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Release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) from organs of the genitourinary tract in rats
| Content Provider | Semantic Scholar |
|---|---|
| Author | Santicioli, Paolo Maggi, Carlo A. Geppetti, Pierangelo Bianco, Elena Del Meli, Alberto |
| Copyright Year | 1988 |
| Abstract | Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) was detected in the rat urinary bladder, ureter and vas deferens and was depleted by systemic capsaicin desensitization. Exposure to capsaicin in vitro produced a prompt increase in CGRP-LI outflow in superfusates of these tissues, while a second application of the drug was ineffective indicating desensitization. These findings provide further evidence for a transmitter role of CGRP from peripheral endings of sensory nerves and the involvement of CGRP-LI in the specific motor response to capsaicin in the rat genitourinary tract. |
| Starting Page | 197 |
| Ending Page | 201 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0304-3940(88)90060-2 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0304394088900602 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0304394088900602?dgcid=api_sd_search-api-endpoint |
| PubMed reference number | 3263593 |
| Alternate Webpage(s) | https://doi.org/10.1016/0304-3940%2888%2990060-2 |
| Journal | Medline |
| Volume Number | 92 |
| Journal | Neuroscience Letters |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
