NDLI: Hypoalbuminemia in critically ill children.

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Hypoalbuminemia in critically ill children.

Content Provider	Semantic Scholar
Author	Horowitz, Ira N. Tai, K.
Copyright Year	2007
Abstract	OBJECTIVE To evaluate whether hypoalbuminemia on admission is a predictor of adverse outcome in critically ill children. DESIGN Retrospective medical record review. SETTING A 14-bed medical and surgical pediatric intensive care unit (PICU). PARTICIPANTS All patients admitted to the PICU from January 1, 1998, through December 31, 2000, under the care of the PICU team or trauma service and whose albumin level was measured were potential subjects. One hundred fifty-five patients were divided into 4 groups on the basis of age and appropriate albumin level for that age group. The groups of hypoalbuminemic patients were combined (hypoalbuminemia group) and compared with the combined group of patients with albumin levels above the reference cutoff (normal albumin level group). EXPOSURE Serum albumin level. MAIN OUTCOME MEASURES Length of PICU and hospital stays, receipt and length of ventilatory support, survival, pediatric risk of mortality score, mortality risk, and number of organ failures. RESULTS Controlling for mortality risk, the hypoalbuminemia group had a longer average stay in the PICU (8.08 vs 4.41 days; 95% confidence interval [CI] for difference, 1.02-6.32) and the hospital (11.36 vs 6.63 days; 95% CI for difference, 1.31-8.16) than did the normal albumin level group. The hypoalbuminemia group had a lower survival rate (odds ratio, 0.10; 95% CI, 0.02-0.46) and a higher number of organ failures (1.38 vs 0.65; 95% CI for difference, 0.40-1.04). CONCLUSION Admission hypoalbuminemia is a significant marker of morbidity and mortality in critically ill children.
Starting Page	10
Ending Page	23
Page Count	14
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://archpedi.jamanetwork.com/journals/PEDS/articlepdf/571450/poa70052_1048_1052.pdf
PubMed reference number	17984406v1
Volume Number	161
Issue Number	11
Journal	Archives of pediatrics & adolescent medicine
Language	English
Access Restriction	Open
Subject Keyword	Confidence Intervals Critical Illness Hypoalbuminemia Medical Records Morbidity - disease rate Multiple Organ Failure Organ of Corti structure Patients Pediatric intensive care unit Wounds and Injuries
Content Type	Text
Resource Type	Article

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