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Ayur-informatics: Establishing an in-silico -ayurvedic medication for Alzheimer's disease
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gore, Mohini Bagchi, Preenon Kar, Ajit Kumar Mumbai, Navi |
| Copyright Year | 2010 |
| Abstract | Alzheimer's disease is an incurable, degenerative, and terminal disease. It is associated with mutations in Amyloid Precursor Protein (APP), Presenilin 1 (PS1), Presenilin 2 (PS2), or Apolipoprotein E (APOE). 3D structures of these 4 proteins were generated using Homology Modeling. Active compounds of medicinal herbs- Canscora decussate , Nardostachys jatamansi and Mucuna pruriens were selected as these three herbs have properties of memory enhancement. Chemical structures of the active component of these herbs were drawn using chemsketch, combined & converted to *.pdb. The four proteins were successfully docked with Canscora decussate - Nardostachys jatamansi -Mucuna pruriens's active component combination. Keywords- Alzheimer's disease, Ayurveda, Canscora decussate , Nardostachys jatamansi, Mucuna pruriens, Drug designing |
| Starting Page | 33 |
| Ending Page | 37 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.9735/0975-3087.2.1.33-37 |
| Volume Number | 2 |
| Alternate Webpage(s) | https://bioinfopublication.org/files/articles/IJBR_2_1_6.pdf |
| Alternate Webpage(s) | https://doi.org/10.9735/0975-3087.2.1.33-37 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
