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Correlation between Dermatophagoides pteronyssinus and Dermatophagoides farinae in house dust mites in chronic urticaria.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sumimoto, Akiko Ishizu, Ken-Ichi Takahashi, Hisaho Yamada, Shizuru Numata, Tsutomu Yamamoto, Shoso Yamura, Takuso Ishii, Asagoro |
| Copyright Year | 1981 |
| Abstract | One hundred and thirty-eight patients with chronic urticaria were tested intradermally with Dermatophagodes pteronyssinus and Dermatophagoides f arinae allergens. None had any past history of other atopic diseases. The percentage of cases which gave positive skin reactions to these mite allergens was larger in chronic urticarial patients than in normal healthy subjects. A significant correlation was observed between the magnitude of skin reactions to D. pteronyssinus and to D. farinae. The results suggest that D. pteronyssinus and D. farinae may play a role in chronic urticaria and that there may be cross allergenicity between D. pteronyssinus and D. f arinae. 247 INTRODUCTION phagoides pteronyssinus is also an important allergen in respiratory allergy in Japan". It is well known that a mite is one of the important allergens in respiratory allergy. In previous studies, we demonstrated that mite may also have an important role in chronic urticaria 1 3>. The percentage of 2 + or 3 + skin reaction to mite allergen was markedly higher in chronic urticarial patients than in normal healthy subjects2>. In the previous investigations, the extract from Dermatophagodes farinae was used as a mite allergen for skin test. Kabasawa et al. showed that DermatoIn the present study, therefore, in order to investigate the role of D. pteronyssinus and correlation between skin reactivity to D. pteronyssinus and to D. f arinae in chronic urticaria, skin test using these allergens was performed in 138 patients with chronic urticaria of unidentified causes. MATERIALS AND METHODS Patients: One hundred and thirty-eight pa*' tt5G:t:n:tt. 9(tt~::::.. :fi:Jt: oo = mtt:•~~~=-:!oH-~!ir"Jm 3t'.::. q:,17)-\" ?" ~ a '7 ~~.::. c:? 7" ~ a '7 3t' .::.17)m~t=. "'?\, \-c 248 A. Sumimoto et al. tients (ages 3 to 82) of both sexes with chronic urticaria were randomly selected for the present investigation. The cause was not identifiable from the histories. None had any past history of other atopic diseases, such as allergic bronchial asthma, allergic rhinitis or atopic dermatitis. The diagnosis of chronic urticaria was established on clinical grounds, the duration being not less than three months. Allergens: D. f arinae allergen was supplied by Torii Pharmaceutical Company (Tokyo}. D. pteronyssinus allergen was prepared from cultured D. pteronyssinus by the method of Ishii et al5>. The concentrations. of D. pteronyssinus · and D. f arin.ae allergens fol;' skin tests were 2. 5 μg/ml and 7. 7 μg/ml respectively. Skin test: Skin tests were done on the inner surfaces of the forearms by injecting intradermally 0. 02 ml of an ·allergen solution. The reactions were read 15 minutes after injection. Skin test grading was based on measurement of the diameter of the wheal using the following criteria: negative, no difference from a ·diluent control; 1 +, s9 mm wheal; 2+, 10 to 14 mm wheal; 3 +, ~15 mm wheal. The magnitude of skin reactions to D. pteronyssinus and D. f arinae. allergens was compared in the same individual. |
| File Format | PDF HTM / HTML |
| PubMed reference number | 7298373 |
| Journal | Medline |
| Volume Number | 30 |
| Issue Number | 3 |
| Alternate Webpage(s) | http://ir.lib.hiroshima-u.ac.jp/files/public/3/38421/20151023104928234169/HiroshimaJMedSci_30_247.pdf |
| Journal | Hiroshima journal of medical sciences |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
