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Rh(iii)-catalyzed alkynylation: synthesis of functionalized quinolines from aminohydrazones.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kumar, Pradeep Garg, Vineeta Kumar, M. Punarjeevan Verma, Akhilesh K. |
| Copyright Year | 2019 |
| Abstract | Rhodium-catalyzed, chemo- and regioselective synthesis of functionalized quinolines using 2-aminohydrazones and terminal alkynes has been described. The reaction is oxidant/base-free and tolerates a wide variety of functional groups and has been successfully extended with 1,3 and 1,4-bis(phenylethynyl)benzenes to afford 1,3- and 1,4-bis(4-methylquinolin-2-yl)benzenes and 2-(3/4-ethynylphenyl)-4-methylquinolines. Furthermore, the control experiment supports the proposed reaction mechanism. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c9cc06205j |
| PubMed reference number | 31544174 |
| Journal | Medline |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c9/cc/c9cc06205j/c9cc06205j1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c9cc06205j |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
