NDLI: Cervical shedding of cytomegalovirus in human immunodeficiency virus type 1-infected women.

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Cervical shedding of cytomegalovirus in human immunodeficiency virus type 1-infected women.

Content Provider	Semantic Scholar
Author	Mostad, Sara B. Ryncarz, A. J. Overbaugh, Julie M. Chohan, Bhavna H. Bwayo, Job Joab Corey, Lawrence
Copyright Year	1999
Abstract	Cervical shedding of cytomegalovirus (CMV) is important in transmission of CMV to exposed sexual partners and neonates. We evaluated prevalence and correlates of CMV DNA shedding in cervical secretions from a large cohort of HIV-1-seropositive women. Using polymerase chain reaction (PCR) assays, CMV DNA was detected in 183 (59%) cervical swab samples from 311 women. Cervical shedding of CMV DNA was significantly associated with shedding of HIV-1 DNA (odds ratio 1.8; 95% confidence interval 1.1-2.8). CMV shedding was also more frequent in women with Neisseria gonorrhoeae and Trichomonas vaginalis infections, but these associations were not statistically significant. Cervical shedding of CMV in HIV-1-infected women is very frequent and may reflect higher risk of transmission to sexual partners and neonates than previously appreciated.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://erepository.uonbi.ac.ke:8080/xmlui/bitstream/handle/11295/28050/Abstract.pdf;sequence=2
PubMed reference number	10534728v1
Volume Number	59
Issue Number	4
Journal	Journal of medical virology
Language	English
Access Restriction	Open
Subject Keyword	Bodily secretions Cervix Mucus Confidence Intervals Cytomegalovirus Infections Fifty Nine HIV Infections Immunologic Deficiency Syndromes Infant, Newborn Neck Physiological Sexual Disorders Polymerase Chain Reaction
Content Type	Text
Resource Type	Article

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