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C2-Symmetric Chiral Bis(thiazoline) and Bis(oxazoline) Ligands and Their Application in the Catalytic Asymmetric Allylic Alkylation.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Du, Da-Ming Xia, Qing |
| Copyright Year | 2004 |
| Abstract | SYNTHESIS 2004, No. 2, pp 0221–0226xx.xx.2004 Advanced online publication: 13.01.2004 DOI: 10.1055/s-2004-815917; Art ID: F09503SS © Georg Thieme Verlag Stuttgart · New York Abstract: A series of novel C2-symmetric bis(thiazoline) ligands with dibenzo[a,c]cycloheptadiene backbone as the substituent on the thiazoline ring were synthesized using the simple reagent phosphorus pentasulfide, and their application in catalytic allylic alkylation was investigated by comparison with the corresponding bis(oxazolines). Palladium-bis(oxazoline) complexes furnished good enantioselectivity (up to 87% ee), while bis(thiazolines) only gave up to moderate enantioselectivity (56% ee) with CH2Cl2 as solvent. Preliminary explanation of the catalysis mechanism is given for the difference of two types of Pd(0)-ligand complexes. |
| Starting Page | 221 |
| Ending Page | 226 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/chin.200423037 |
| Volume Number | 35 |
| Alternate Webpage(s) | http://www.xiuzhengrd.com/ejournals/pdf/synthesis/doi/10.1055/s-2004-815917.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/chin.200423037 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
