NDLI: Adsorption of Proteins to Thin-Films of PDMS and Its Effect on the Adhesion of Human Endothelial Cells.

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Adsorption of Proteins to Thin-Films of PDMS and Its Effect on the Adhesion of Human Endothelial Cells.

Content Provider	Semantic Scholar
Author	Chumbimuni-Torres, Karin Y. Mfuh, Adelphe M. Castro-Guerrero, Carlos Silva, Maria Fernanda Gouveia Da Bizios, Rena
Copyright Year	2011
Abstract	This paper describes a simple and inexpensive procedure to produce thin-films of poly(dimethylsiloxane). Such films were characterized by a variety of techniques (ellipsometry, nuclear magnetic resonance, atomic force microscopy, and goniometry) and used to investigate the adsorption kinetics of three model proteins (fibrinogen, collagen type-I, and bovine serum albumin) under different conditions. The information collected from the protein adsorption studies was then used to investigate the adhesion of human dermal microvascular endothelial cells. The results of these studies suggest that these films can be used to model the surface properties of microdevices fabricated with commercial PDMS. Moreover, the paper provides guidelines to efficiently attach cells in BioMEMS devices.
Starting Page	706
Ending Page	714
Page Count	9
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.rsc.org/suppdata/ra/c1/c1ra00198a/c1ra00198a.pdf
PubMed reference number	25068038v1
Volume Number	1
Issue Number	4
Journal	RSC advances
Language	English
Access Restriction	Open
Subject Keyword	BioMEMS Cattle Microscopy, Atomic Force Serum Albumin, Bovine
Content Type	Text
Resource Type	Article

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