NDLI: Sequence of genome segments 1, 2, and 3 of the grass carp reovirus (Genus Aquareovirus, family Reoviridae).

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Sequence of genome segments 1, 2, and 3 of the grass carp reovirus (Genus Aquareovirus, family Reoviridae).

Content Provider	Semantic Scholar
Author	Fang, Qing Attoui, Houssam Cantaloube, Jean François Biagini, Philippe Zhu, Zhengmao Micco, Philippe De Lamballerie, Xavier De
Copyright Year	2000
Abstract	The genome segments 1, 2, and 3 of the grass carp reovirus (GCRV), a tentative species assigned to genus Aquareovirus, family Reoviridae, were sequenced. The respective segments 1, 2, and 3 were 3949, 3877, and 3702 nucleotides long. Conserved motifs 5' (GUUAUUU) and 3' (UUCAUC) were found at the ends of each segment. Each segment contains a single ORF and the negative strand does not permit identification of consistent ORFs. Sequence analysis revealed that VP2 is the viral polymerase, while VP1 might represent the viral guanylyl/methyl transferase (involved in the capping process of RNA transcripts) and VP3 the NTPase/helicase (involved in the transcription and capping of viral RNAs). The highest amino acid identities (26-41%) were found with orthoreovirus proteins. Further genomic characterization should provide insight about the genetic relationships between GCRV, aquareoviruses, and orthoreoviruses. It should also permit to precise the taxonomic status of these different viruses.
File Format	PDF HTM / HTML
DOI	10.1006/bbrc.2000.3215
PubMed reference number	10924351
Journal	Medline
Volume Number	274
Issue Number	3
Alternate Webpage(s)	http://ir.ihb.ac.cn/bitstream/152342/10104/1/Sequence%20of%20genome%20segments%201,%202,%20and%203%20of%20the%20grass%20carp%20reovirus%20(genus%20Aquareovirus,%20family%20Reoviridae)%20.pdf
Alternate Webpage(s)	https://doi.org/10.1006/bbrc.2000.3215
Journal	Biochemical and biophysical research communications
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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