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pH-sensitive intracellular photoluminescence of carbon nanotube-fluorescein conjugates in human ovarian cancer cells.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chen, Michelle T. Gomez, L. M. Ishikawa, Fumiaki N. Vernier, P. Thomas Zhou, Ce Gundersen, Martin A. |
| Copyright Year | 2009 |
| Abstract | To add to the understanding of the properties of functionalized carbon nanotubes in biological applications, we report a monotonic pH sensitivity of the intracellular fluorescence emission of single-walled carbon nanotube-fluorescein carbazide (SWCNT-FC) conjugates in human ovarian cancer cells. Light-stimulated intracellular hydrolysis of the amide linkage and localized intracellular pH changes are proposed as mechanisms. SWCNT-FC conjugates may serve as intracellular pH sensors. |
| Starting Page | 295101 |
| Ending Page | 295101 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://nanolab.usc.edu/assets/001/87258.pdf |
| PubMed reference number | 19567963v1 |
| Alternate Webpage(s) | https://doi.org/10.1088/0957-4484/20/29/295101 |
| DOI | 10.1088/0957-4484/20/29/295101 |
| Journal | Nanotechnology |
| Volume Number | 20 |
| Issue Number | 29 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Carbon-Carbon Lyases Fluorescence Immunostimulating conjugate (antigen) Malignant neoplasm of ovary Nanotubes Nanotubes, Carbon cancer cell fluorescein sodium ovarian neoplasm |
| Content Type | Text |
| Resource Type | Article |
