Loading...
Please wait, while we are loading the content...
Similar Documents
Coincidence of B-cell chronic lymphocytic leukemia and cutaneous T-cell lymphoma (mycosis fungoides): immunologic characterization by monoclonal antibodies.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sheibani, Kaveh Forman, Stephen J. Winberg, Carina Rappaport, Henry |
| Copyright Year | 1983 |
| Abstract | Although rare cases of chronic lymphocytic leukemia (CLL) of the T-cell type have been reported, CLL is more commonly found to be a neoplastic lymphoproliferative disease of B-cell origin. In this article, we describe a patient with long-standing CLL that was immunologically shown to be of the B-cell type, who, during the course of his disease, developed cutaneous T-cell lymphoma (CTCL), which was shown to be of the helper/inducer subtype. The neoplastic lymphoid cells in the skin infiltrate differed morphologically and immunologically from those in the peripheral blood. The occurrence of CTCL during this patient's clinical course represents a second neoplasm arising from a different cell line, rather than a tissue manifestation of the patient's CLL. To our knowledge, this is the first report in which the occurrence of CTCL is documented in a patient with immunologically known B-cell CLL. In addition to establishing the presence of B-cell CLL and CTCL of the helper/inducer T-cell type in the same patient, this case report demonstrates the usefulness and necessity of evaluating lymphoproliferative disorders by means of a multidisciplinary approach. |
| File Format | PDF HTM / HTML |
| DOI | 10.1182/blood.V62.6.1176.bloodjournal6261176 |
| PubMed reference number | 6416333 |
| Journal | Medline |
| Volume Number | 62 |
| Issue Number | 6 |
| Alternate Webpage(s) | http://www.bloodjournal.org/content/bloodjournal/62/6/1176.full.pdf?sso-checked=true |
| Alternate Webpage(s) | https://doi.org/10.1182/blood.V62.6.1176.bloodjournal6261176 |
| Journal | Blood |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
