Loading...
Please wait, while we are loading the content...
Similar Documents
Coincidence of B-cell chronic lymphocytic leukemia and cutaneous T-cell lymphoma (mycosis fungoides): immunologic characterization by monoclonal antibodies
| Content Provider | Scilit |
|---|---|
| Author | Sheibani, K. Forman, Sj Winberg, Cd Rappaport, H. |
| Copyright Year | 1983 |
| Description | Although rare cases of chronic lymphocytic leukemia (CLL) of the T-cell type have been reported, CLL is more commonly found to be a neoplastic lymphoproliferative disease of B-cell origin. In this article, we describe a patient with long-standing CLL that was immunologically shown to be of the B-cell type, who, during the course of his disease, developed cutaneous T-cell lymphoma (CTCL), which was shown to be of the helper/inducer subtype. The neoplastic lymphoid cells in the skin infiltrate differed morphologically and immunologically from those in the peripheral blood. The occurrence of CTCL during this patient's clinical course represents a second neoplasm arising from a different cell line, rather than a tissue manifestation of the patient's CLL. To our knowledge, this is the first report in which the occurrence of CTCL is documented in a patient with immunologically known B-cell CLL. In addition to establishing the presence of B-cell CLL and CTCL of the helper/inducer T-cell type in the same patient, this case report demonstrates the usefulness and necessity of evaluating lymphoproliferative disorders by means of a multidisciplinary approach. |
| Related Links | https://ashpublications.org/blood/article-pdf/62/6/1176/212330/1176.pdf |
| Ending Page | 1181 |
| Page Count | 6 |
| Starting Page | 1176 |
| DOI | 10.1182/blood.v62.6.1176.bloodjournal6261176 |
| Journal | Blood |
| Issue Number | 6 |
| Volume Number | 62 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1983-12-01 |
| Access Restriction | Open |
| Subject Keyword | Dermatology Antibodies Leukemia Cutaneous Lymphocytic Cll Ctcl Course Cell Type Neoplastic Immunologically Journal: Blood (Vol- 87, Issue- 6) |
| Content Type | Text |
| Resource Type | Article |
