NDLI: Acute coronary syndromes in black South African patients with human immunodeficiency virus infection

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Acute coronary syndromes in black South African patients with human immunodeficiency virus infection

Content Provider	Semantic Scholar
Author	Becker, Anthony
Copyright Year	2011
Abstract	Objectives: To describe the recent increase in acute coronary syndromes among urban black South Africans in Soweto. Design: Cross-sectional study in 2004 and comparison with data from 1975-80. Setting: Chris Hani Baragwanath Hospital, Soweto. Participants: Patients admitted with a diagnosis of troponin positive acute coronary syndrome (ACS) in 2004, to Coronary Care Unit (CCU) and patients admitted with a diagnosis of acute myocardial infarction (AMI) in 1975-80. Results: We identified 154 patients with ACS in 2004. Of these 64 (42%) were black, 50 (32%) were white and 40 (26%) Asian. Between 1975 and 80, 54 patients were diagnosed with AMI (50 were black). Mean age in 2004 was 56 years and most were men (110; 71%). Risk factor prevalence was high in 2004. Black patients tended to be younger, less likely to have diabetes than Asians, and much less likely to have a family history of coronary artery disease. Black patients were more likely to have only one coronary artery affected by atherosclerosis than were white patients (48% vs 26%, p=0.07). Eight patients died in 2004 (5%) and eight in 1975-80 (15%). Conclusion: The annual incidence of ACS among black Africans has increased rapidly in Soweto. There seem to be significant dif- ferences in risk factor profile and extent of coronary arteries involved among the different ethnic groups studied. Continued emergence of coronary artery disease implies a significant additional burden to the health system. KS and CA conceived of the study, supervised data collection, and drafted the paper. CA, LN and AB collected data. DW and SS con- tributed to data analysis and paper drafting. EL analysed data. All authors reviewed the final paper. No funding was used to support this study. ARTICLE Spring 2006 • SA HEART 7 SAHJ Journal Spring 06 10/12/06 3:37 PM Page 7
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://wiredspace.wits.ac.za/bitstream/handle/10539/10580/ABecker%20PHD.pdf;sequence=1
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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