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Psychotic and major neurocognitive disorder secondary to arnold-chiari type II malformation.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hoederath, Linda Jellestad, Lena Jenewein, Josef Boettger, Soenke |
| Copyright Year | 2014 |
| Abstract | Arnold-Chiari malformations (ACM) represent a constellation of related congenital anomalies at the base of the brain. ACM is a very rare disorder with displacement of the cerebellar tonsils caudally into the foramen magnum. To date, the cause of this malformation is unknown, however, there is some evidence for a defect of the paraxial mesoderm resulting in a shallow posterior cranial fossa and brainstem as well as herniation through the foramen magnum (Caldwell et al. 2009). ACM is characterized by four subtypes. A) type I represents a herniation of the cerebellar tonsils into the foramen magnum, B) type II is associated with a myelomeningocele and hydrocephalus, herniation not only of the tonsils, but also the vermis, fourth ventricle, and pons. Morphologically, aqueductal stenosis, hydromelia and cortical dysplasia occur. C) type III is characterized by an encephalocele, the descent of both cerebellum and brainstem into the spine and internal sac, and D) type IV is associated with cerebellar atrophy (Caldwell et al. 2009). There are many somatic complications caused by ACM such as a pain, motor deficits, hand muscular atrophy, lower cranial palsy, cerebellar ataxia, nystagmus, sensory deficits, dysphagia, and dysphonia (Caldwell et al. 2009). In addition, psychiatric comorbidities such as anxiety and mood disorders occur and affect the functioning and quality of life (Bakim et al. 2013, Mestres et al. 2012). To date, only two case reports describe the association with psychosis (Del Casale et al. 2012, Ilankovic et al. 2006) and only one case mentions a secondary major neurocognitive disorder (Mahgoub et al. 2012). |
| Starting Page | 85 |
| Ending Page | 92 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://hrcak.srce.hr/file/239132 |
| PubMed reference number | 25191780v1 |
| Volume Number | 26 |
| Issue Number | 3 |
| Journal | Psychiatria Danubina |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Abducens Nerve Diseases Aclarubicin Anxiety Disorders Aqueductal Stenosis Arnold Chiari Malformation Arnold-Chiari Malformation, Type I Atrophic Brain Stem Cerebellar Ataxia Cerebellar Diseases Cerebellar vermis structure Cerebellum Congenital Abnormality Congenital cerebral hernia Cortical Dysplasia Deglutition Disorders Diploid Cell Dysphonia Fourth ventricle structure HMN (Hereditary Motor Neuropathy) Proximal Type I Hydrocephalus Meningomyelocele Mental disorders Mood Disorders Muscle Neurocognitive Disorders Nystagmus Pain Palatine Tonsil Paraxial Mesoderm Pontine structure Psychologic Displacement Psychotic Disorders Rare Diseases Sensory Neuropathy, Hereditary Structure of foramen magnum Structure of posterior fossa of cranial cavity Subtype (attribute) spindle assembly checkpoint |
| Content Type | Text |
| Resource Type | Article |
