Orthostatic intolerance and syncope associated with Chiari type I malformation.

Content Provider	Semantic Scholar
Author	Prilipko, Olga Dehdashti, Amir R. Zaim, Sina Seeck, Margitta
Copyright Year	2005
Abstract	The Chiari type I malformation (CM1) is characterized by herniation of cerebellar tonsils to at least 3-5 mm below the plane of foramen magnum and can present with a wide variety of clinical symptoms, frequently including occipital headaches, secondary to bulbar and/or medullary distress. Rarely, syncopal episodes have also been described and attributed to either compression of the midbrain ascending reticular system, or vascular compromise (vertebrobasilar artery compression, hypotension). We report the first case of a CM1 patient with frequently recurring syncope due to postural orthostatic tachycardia syndrome (POTS), a form of orthostatic intolerance, whose symptoms resolved completely after surgical intervention. It is important to stress that it is not clear whether the described association of POTS and CM1 in our patient is a fortuitous finding in an isolated case or a reflection of a more systematic association between the two pathologies.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://jnnp.bmj.com/content/jnnp/76/7/1036.full.pdf
Alternate Webpage(s)	http://jnnp.bmj.com/content/jnnp/76/7/1034.full.pdf
PubMed reference number	15965223v1
Volume Number	76
Issue Number	7
Journal	Journal of neurology, neurosurgery, and psychiatry
Language	English
Access Restriction	Open
Subject Keyword	Arnold Chiari Malformation Arnold-Chiari Malformation, Type I Cluster Headache Compression Congenital Abnormality Hernia Medulla Oblongata Midbrain structure Patients Postural Orthostatic Tachycardia Syndrome Shy-Drager Syndrome Structure of foramen magnum Syncope Vascular calcification anatomical bulb
Content Type	Text
Resource Type	Article