NDLI: Intestinal IL-17 Expression in Canine Inflammatory Bowel Disease

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Intestinal IL-17 Expression in Canine Inflammatory Bowel Disease

Content Provider	Semantic Scholar
Author	Azuma, Yoko Kuramoto
Copyright Year	2017
Abstract	The gastrointestinal tract is crucial for the immunological system in host defense in addition to food intake, food digestion, and nutrient absorption within humans and animals. Epithelium barrier in the intestine plays to block pathogens from the lumen. Inflammatory bowel diseases (IBDs) in dogs, as well as humans, are characterized by dysregulated intestinal inflammation and mucosal tissue damage in parts of the gastrointestinal tract [9, 11-13, 15, 18, 24, 28]. Regarding of histologic criteria, ulcerative colitis (UC) and Crohn’s disease (CD) are the two types of human IBD. Despite having a common basis in over responsiveness to mucosal antigens, UC and CD have considerably different pathophysiologies. In contrast, IBD in dogs divided into the several types by histological criteria of inflammatory infiltrate such as neutrophilic, eosinophilic, lymphocytic, plasmacytic and granulomatous. However, little is known whether these types reveal the common basis or different basis. Some reports show the pathology is different between humans and dogs, whereas other reports show common mucosal immune system between human and dogs [1, 6, 8, 19].
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://scidoc.org/articlepdfs/IJVHSR/IJVHSR-2332-2748-05-301.pdf
Language	English
Access Restriction	Open
Subject Keyword	Canis familiaris Crohn Disease Digestion Gastrointestinal Diseases Gastrointestinal tract structure Immune system Inflammatory Bowel Diseases Intestinal Diseases Intestinal Wall Tissue Intestines Ion beam deposition Irritable Bowel Syndrome Mucous Membrane Plasma Cells Responsiveness Soft Tissue Injuries Structure of lumen of body system Tract (literature) UC Browser Ulcer Ulcerative Colitis host defense neutrophilic
Content Type	Text
Resource Type	Article

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