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Activation of membrane-bound adenylate cyclase by glucagon in Neurospora crassa.
| Content Provider | Semantic Scholar |
|---|---|
| Author | FlawiĆ”, Mirtha M. Torres, Hector Norberto |
| Copyright Year | 1972 |
| Abstract | Membrane-bound adenylate cyclase in Neurospora crassa is activated by glucagon. Half-maximal effect is observed at hormone concentrations of about 10 nM. After solubilization of the enzyme with Lubrol-PX, the glucagon effect is lost. Incubation of neurospora cells with glucagon leads to a decrease in the activity of glycogen synthetase (EC 2.4.1.11) and to an increase in the activity of glycogen phosphorylase (EC 2.4.1.1) and in the rate of glycogenolysis. |
| Starting Page | 5624 |
| Ending Page | 5633 |
| Page Count | 10 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.pnas.org/content/69/10/2870.full.pdf |
| PubMed reference number | 4263508v1 |
| Volume Number | 69 |
| Issue Number | 10 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adenylate Adenylyl Cyclase 9 GCG gene Glucagon Glycogen (Starch) Synthase Glycogenolysis L-Epicatechin Ligase Neurospora sitophila Ab.IgE:ACnc:Pt:Ser:Qn Phosphorylases Tissue membrane |
| Content Type | Text |
| Resource Type | Article |