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Proniosomal gel : transdermal drug delivery : A review
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wilson, Vincent H. Krishnakumar, K. Dineshkumar |
| Copyright Year | 2017 |
| Abstract | Drug delivery systems using colloidal particulate carriers such as liposomes or niosomes have distinct advantages over conventional dosage forms because the particles can act as drug containing reservoirs. Modification of the particle composition or surface can adjust the affinity for the target site and the drug release rate, and the slowing drug release rate may reduce the toxicity of drug.Transdermal is a non-invasive mode of drug delivery route. It is an attractive route of drug administration to maintain drug levels in the blood for a sustained period of time locally and systemically.Proniosomes are well documented for transdermal drug delivery and preferred over other vesicular systems because they are biodegradable, biocompatible, non-toxic, possess skin penetration ability and prolong the release of drugs by acting as depot in deeper layers of skin.Proniosomes are dry formulation of water-soluble carrier particles coated with surfactant which can be dehydrated to form niosomal dispersion immediately before use on brief agitation in hot aqueous media within minutes.The review provides an idea about the design and development of proniosomal gel (PNG)and its properties. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.ijcps.com/files/vol8issue1/10.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
