NDLI: Exceptional biocompatibility of 3D fibrous scaffold for cardiac tissue engineering fabricated from biodegradable polyurethane blended with cellulose

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Exceptional biocompatibility of 3D fibrous scaffold for cardiac tissue engineering fabricated from biodegradable polyurethane blended with cellulose

Content Provider	Semantic Scholar
Author	Su, Wei-Fang Ho, Chun-Chih Shih, T. Wang, Chen-Hua Yeh, Chun-Hao
Copyright Year	2016
Abstract	ABSTRACT The auhtors report 3D biomimetic scaffolds using polymer blend of polyurethane and cellulose for cardiac tissue engineering. The biocompatible and biodegradable polyurethane is designed, synthesized and characterized. By incorporating 10 wt% of naturally ordered cellulose into the polyurethane and electrospinning them into 3D scaffold, the scaffold exhibits good biocompatibility and mechanical property to support and accommodate constant cycles of contraction/expansion of cardiac tissue. The biocompatibility is further improved using scaffold fabricated from aligned fibers due to synergistic effects between cells and ordered macromolecules. The anisotropic structured scaffold is mimicked the extracellular matrix and has therapeutic potential in reconstruction of damaged myocardium. GRAPHICAL ABSTRACT
Starting Page	703
Ending Page	711
Page Count	9
File Format	PDF HTM / HTML
DOI	10.1080/00914037.2016.1157802
Volume Number	65
Alternate Webpage(s)	http://www.mse.ntu.edu.tw/~frontier/2016,%20International%20Journal%20of%20Polymeric%20Materials%20and%20Polymeric%20Biomaterials,%2065(14),%20703-711.pdf
Alternate Webpage(s)	https://doi.org/10.1080/00914037.2016.1157802
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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