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How fungi keep time: circadian system in Neurospora and other fungi.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Dunlap, Jay C. Loros, Jennifer J. |
| Copyright Year | 2006 |
| Abstract | The circadian system in Neurospora remains a premier model system for understanding circadian rhythms, and evidence has now begun to accumulate suggesting broad conservation of rhythmicity amongst the filamentous fungi. A well-described transcription-translation-based negative feedback loop involving the FREQUENCY, WHITE COLLAR-1 and WHITE COLLAR-2 proteins is integral to the Neurospora system. Recent advances include descriptions of the surprisingly complex frequency transcription unit, an enhanced appreciation of the roles of kinases and their regulation in the generation of the circadian rhythm and their links to the cell cycle, and strong evidence for an additional WHITE COLLAR-associated feedback loop. Documentation of sequence homologs of integral circadian and photoresponsive proteins amongst the 42 available sequenced fungal genomes suggests unexpected roles for circadian timing among both pathogens and saprophytes. |
| Starting Page | 90 |
| Ending Page | 102 |
| Page Count | 13 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.davidmoore.org.uk/21st_Century_Guidebook_to_Fungi_PLATINUM/REPRINT_collection/Dunlap_Loros_Circadian_timing.pdf |
| PubMed reference number | 17064954v1 |
| Volume Number | 9 |
| Issue Number | 6 |
| Journal | Current opinion in microbiology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cellular Phone Circadian Rhythms Description Filamentous fungus Fungi Genome Genome, Fungal Neurospora Sleep Disorders, Circadian Rhythm saprophyte |
| Content Type | Text |
| Resource Type | Article |
