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Phosphatidylinositol 4,5-bisphosphate phosphodiesterase in higher plants.
| Content Provider | Semantic Scholar |
|---|---|
| Author | W. C. McM U. R. R. A. Y. Irvine, Robin F. |
| Copyright Year | 1988 |
| Abstract | A phospholipase C which hydrolyses phosphatidylinositol 4,5-bisphosphate to release inositol trisphosphate was detected in a sedimentable fraction from celery and from some other higher plants. The particulate enzyme also hydrolyses phosphatidylinositol, whereas the soluble phosphatidylinositol phosphodiesterase described previously [Irvine, Letcher & Dawson (1980) Biochem. J. 192, 279-283] acts only on phosphatidylinositol, and we were unable to detect activity of this soluble activity on phosphatidylinositol 4,5-bisphosphate. Activity of the particulate enzyme is markedly enhanced in the presence of deoxycholate, but not of other detergents; the particulate enzyme can also be solubilized by extraction with deoxycholate. |
| Starting Page | 1 |
| Ending Page | 9 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.biochemj.org/content/ppbiochemj/249/3/877.full.pdf |
| PubMed reference number | 2833230v1 |
| Volume Number | 249 |
| Issue Number | 3 |
| Journal | The Biochemical journal |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Deoxycholate Detergents Particulate (substance) Phosphatidylinositol 4,5-Diphosphate Phospholipase negative regulation of inositol biosynthetic process |
| Content Type | Text |
| Resource Type | Article |
