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Acute pancreatitis during all-trans-retinoic acid treatment for acute promyelocytic leukemia in a patient without overt hypertriglyceridemia.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Teng, H. J. Bai, Li-Yuan Chao, T. C. Wang, W. S.-Y. Chen, Po-Min |
| Copyright Year | 2005 |
| Abstract | All-trans-retinoic acid (ATRA) has been successfully used in the treatment of acute promyelocytic leukemia (APL). One of its adverse effects is acute pancreatitis. In the literature, a proposed cause of acute pancreatitis is hypertriglyceridemia. Here, we present the case of a 45-year-old male with APL, treated with ATRA combined with induction chemotherapy (cytarabine and idarubicin), who developed acute pancreatitis without overt hypertriglyceridemia. This finding suggests that hypertriglyceridemia might not be the sole contributing factor in the pathogenesis of ATRA-induced acute pancreatitis and that attention should be paid to the possibility that ATRA treatment causes acute pancreatitis in the absence of overt hypertriglyceridemia. |
| Starting Page | 1 |
| Ending Page | 13 |
| Page Count | 13 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://watermark.silverchair.com/hyi027.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAZ8wggGbBgkqhkiG9w0BBwagggGMMIIBiAIBADCCAYEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMtwDGuvh8-KDNQuMaAgEQgIIBUgehSUXh6-Cs7CwubaG-KH2KmiwxBALX0jhPAMrAEhaNrrBDbD-Qui0h9_SMX8mi524lmAVwDn4S4TYWZi1VYK_AAjgMgAdKgZx_IRE_wQLedXnSiO492C3mtJ0ZImJMjgzelq-v17VKjVUJ1-qnNgYTDjTKJnmGTsLRSxVfY4UGiGaOKklUpUYFOpMGdaYCrwRjwNLNngwMWPCo1fui09ORESd1yEB3ZoHgEjGMrte3yDY1G36pHk3TwENDKVQP3KjNRLSjwsVLqFIXBs5bq19-r_1pb4uyeIUidEwt0TkT_YeyV53f-UDsOVbMe2qa9_Bh-DUD-azcXO7jcNCIpxat0lyiQuPX6ZHyIgE0W4jmDwSE4rbFxZAcxggbgqwz2feU4WLQI0n8Us23rRvAOH2KQbMVfYb0UKkFR53kvvsWLwPgdnUikrSKJpMerEMCD0o0 |
| PubMed reference number | 15709095v1 |
| Volume Number | 35 |
| Issue Number | 2 |
| Journal | Japanese journal of clinical oncology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acute Promyelocytic Leukemia Acute pancreatitis Contribution Cytarabine Hypertriglyceridemia Idarubicin Leukemia, Myelocytic, Acute Patients Tretinoin |
| Content Type | Text |
| Resource Type | Article |
