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The effects of N-acetylaspartylglutamate and distribution of N-acetylaspartylglutamate-like immunoreactivity in the rat somatosensory thalamus
| Content Provider | Semantic Scholar |
|---|---|
| Author | Henderson, Zaineb Salt, Thomas E. |
| Copyright Year | 1988 |
| Abstract | The ventrobasal thalamus and adjacent regions were stained for the presence of N-acetylaspartylglutamate-like immunoreactivity. Immunoreactive axonal terminals were observed in this area and also in certain non-specific thalamic nuclei, the reticular thalamic nucleus and the lateral geniculate nucleus. Stained somata were found in the habenula, centrolateral thalamic nucleus and reticular thalamic nucleus. Iontophoretically applied N-acetylaspartylglutamate had variable, although predominantly inhibitory, actions on ventrobasal thalamus neurons. These results indicate that N-acetylaspartylglutamate is unlikely to be the neurotransmitter of ascending somatosensory afferents, but do not rule out the possibility that it has some other neurotransmitter or neuromodulator role in the ventrobasal thalamus. |
| Starting Page | 899 |
| Ending Page | 906 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0306-4522(88)90043-7 |
| PubMed reference number | 3405432 |
| Journal | Medline |
| Volume Number | 25 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0306452288900437 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0306452288900437?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0306-4522%2888%2990043-7 |
| Journal | Neuroscience |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |