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Simultaneous near-infrared and green fluorescence from single conjugated polymer dots with aggregation-induced emission fluorogen for cell imaging.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chen, Sitong Cui, Shuang Du, Rongxin Liu, Ming Tsai, Wei-Kai Guo, Fengyun Wu, Qiong Fei Zhao, Liancheng Zhang, Yong |
| Copyright Year | 2018 |
| Abstract | Near-infrared fluorescent probes are important and interesting for advanced biological and biomedical applications where the fluorescence technology is employed. Herein, we reported high near-infrared (NIR) fluorescent conjugated polymer dots (Pdots) of two polymers (PTPE-DTNT2 and PTPE-DTNT4) with cross-conjugated aggregation-induced emission fluorogen as the side chain. The photoluminescent quantum yields (PLQYs) of Pdots were up to 31.8% with the near-infrared emission peak of 716 nm, which is among the best values of NIR Pdots reported so far. In addition, Pdots possessed a dual-color emission feature. Thus, dual-color cellular imaging with both Pdots was demonstrated in biological applications; to the best of our knowledge, this is the first reported dual-color cellular imaging with Pdots. The NIR Pdots were also applied in in vivo cytotoxicity analysis and microangiography imaging of zebrafish. We anticipate that NIR Pdots with their dual-color feature will find broad applications in multiplexed biological and biomedical fields. |
| Starting Page | 7871 |
| Ending Page | 7876 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/C8TB02346H |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/tb/c8tb02346h/c8tb02346h1.pdf |
| PubMed reference number | 32255032 |
| Alternate Webpage(s) | https://doi.org/10.1039/C8TB02346H |
| Journal | Medline |
| Volume Number | 6 |
| Issue Number | 47 |
| Journal | Journal of materials chemistry. B |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
