Loading...
Please wait, while we are loading the content...
Similar Documents
Number of Biopsies in Diagnosing Pulmonary Nodules
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wehrschütz, Martin Wehrschuetz, E. Portugaller, Horst Rupert |
| Copyright Year | 2010 |
| Abstract | PURPOSE To determine the number of specimens to be obtained from pulmonary lesions to get the highest possible accuracy in histological work-up. MATERIALS AND METHODS A retrospective evaluation (January 1999 to April 2004) covered 260 patients with thoracic lesions who underwent computer tomography (CT)-guided core-cut biopsy in coaxial technique. All biopsies were performed utilizing a 19 gauge introducer needle and a 20 gauge core-cut biopsy needle. In all, 669 usable biopsies were taken (from 1-5 biopsies in each setting). The specimens were marked sequentially and each biopsy was worked up histologicaly. The biopsy results were correlated to histology after surgery, clinical follow-up or autopsy. The number of biopsies was determined that is necessary to achieve the highest possible accuracy in diagnosing pulmonary lesions. RESULTS In 591 of 669 biopsies (88.3%), there were correct positive results. The overall accuracy was 87.4%. In 193 of 260 (74.2%) patients, a suspected malignancy was confirmed. In 50 of 260 (19.2%) patients, a benign lesion was correctly diagnosed. Seventeen (6.5%) patients were lost to follow-up. The first, second and third biopsies had cumulative accuracies of 63.6%, 89.2% and 91.5%, respectively (P < 0.02). More biopsies did not show any higher impact on accuracy. CONCLUSION For the highest possible accuracy in diagnosing pulmonary lesions by CT-guided core-cut biopsy, at least three usable specimens are recommended to be taken. |
| Starting Page | 9 |
| Ending Page | 14 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 21157523 |
| Volume Number | 4 |
| Journal | Clinical medicine insights. Circulatory, respiratory and pulmonary medicine |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/79/c0/ccrpm-2010-009.PMC2998930.pdf |
| Alternate Webpage(s) | http://insights.sagepub.com/redirect_file.php?fileId=2946&fileType=pdf&filename=2152-CCRPM-Number-of-Biopsies-in-Diagnosing-Pulmonary-Nodules.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Biopsy Chest Follow-Up Report Idiopathic Pulmonary Fibrosis Neoplasms Patients Specimen Tuberculosis, Pulmonary X-Ray Computed Tomography work up |
| Content Type | Text |
| Resource Type | Article |
