Loading...
Please wait, while we are loading the content...
Similar Documents
Short-term exposure to high levels of air pollution as a risk factor for acute isolated pulmonary embolism.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Spiezia, Luca Campello, Elena Bon, Maria Maggiolo, Sara Pelizzaro, Elena Simioni, Paolo |
| Copyright Year | 2014 |
| Abstract | BACKGROUND The association between air pollution exposure and occurrence of venous thromboembolism is a matter of debate. This retrospective case-control study investigated the associations between one month's exposure to elevated levels of different pollutants (i.e. PM10, CO, NOx, O3, SO2, Benzene, Benzoapyrene, Nickel, Lead Arsenic) and the development of acute isolated pulmonary embolism (PE). METHODS The cases included 33 patients consecutively admitted to Padua Hospital with an objectively proven diagnosis of acute unprovoked (i.e. without predisposing conditions) isolated (i.e. without deep vein thrombosis) PE. The control group consisted of 72 consecutive patients with objectively proven acute provoked (i.e. associated to predisposing conditions) isolated PE. Average mean concentrations of pollutants in the month before PE diagnosis were computed by monitors located at 2 different sites throughout the city of Padua, and were obtained from the Regional Agency for Environmental Protection. RESULTS Individuals who had PM10, NOx, Benzene, Benzoapyrene, Cadmium, and Lead exposure equal/above the 2nd tertile, measured in controls, showed a significant increase in the risk of unprovoked PE. In case of PM10 and Benzoapyrene this risk was not affected after adjustment for possible confounders. In fact, in the multivariate logistic regression analysis, the OR values were 5.24 (95% CI: 1.52-18.12) for PM10 and 3.95 (95% CI: 1.06-14.71) for Benzoapyrene exposure in the month before PE diagnosis. CONCLUSIONS Our results, although preliminary, identify short-term (i.e. one month) exposure to elevate levels of air pollutants as a possible risk factor for the development of acute isolated PE. Larger studies are needed to confirm our results. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.thromres.2014.05.011 |
| PubMed reference number | 24909892 |
| Journal | Medline |
| Volume Number | 134 |
| Issue Number | 2 |
| Alternate Webpage(s) | http://www.ethics.it/pubblicazioni/Air%20pollution%20-%20Thrombosis%20Research%20May%202014%20epub.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.thromres.2014.05.011 |
| Journal | Thrombosis research |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
