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Short-Term Air Pollution Exposure and Risk of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Korea: A National Time-Stratified Case-Crossover Study
| Content Provider | MDPI |
|---|---|
| Author | Jung, Yun Jung Kim, Eun Jin Heo, Jung Yeon Choi, Young Hwa Kim, Dae Jung Ha, Kyoung Hwa |
| Copyright Year | 2022 |
| Description | We investigated the association between short-term exposure to air pollution and the risk of acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) in seven metropolitan cities in Korea. We used national health insurance claims data to identify AE-COPD cases in 2015. We estimated short-term exposure to particulate matter (PM) with a diameter of ≤2.5 μm $(PM_{2.5}$), PM with diameters of ≤10 μm $(PM_{10}$), sulfur dioxide $(SO_{2}$), nitrogen dioxide $(NO_{2}$), carbon monoxide (CO), and ozone $(O_{3}$) obtained from the Ministry of Environment. We conducted a time-stratified, case-crossover study to evaluate the effect of short-term exposure to air pollution on hospital visits for AE-COPD, using a conditional logistic regression model. The risk of hospital visits for AE-COPD was significantly associated with interquartile range increases in $PM_{10}$ in a cumulative lag model (lag 0–2, 0.35%, 95% confidence interval (CI) 0.06–0.65%; lag 0–3, 0.39%, 95% CI 0.01–0.77%). The associations were higher among patients who were men, aged 40–64 years, with low household income, and with a history of asthma. However, other air pollutants were not significantly associated with the risk of hospital visits for AE-COPD. Short-term exposure to air pollution, especially $PM_{10}$, increases the risk of hospital visits for AE-COPD. |
| Starting Page | 2823 |
| e-ISSN | 16604601 |
| DOI | 10.3390/ijerph19052823 |
| Journal | International Journal of Environmental Research and Public Health |
| Issue Number | 5 |
| Volume Number | 19 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-02-28 |
| Access Restriction | Open |
| Subject Keyword | International Journal of Environmental Research and Public Health Air Pollution Acute Exacerbation Chronic Obstructive Pulmonary Disease Insurance Claims |
| Content Type | Text |
| Resource Type | Article |
