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Vitamin D deficiency and lower urinary tract symptoms in males above 50 years of age
| Content Provider | Semantic Scholar |
|---|---|
| Author | Elshazly, Mohamed Abdemonem Sultan, Mohamed Farag Aboutaleb, Hamdy Abdelmawla Salem, Shady Mohamed Aziz, Mohamed Sayedahmed Elbaky, Tarek Mohamed Abd Elsherif, Eid Abdelrasoul Gawish, Maher Alajrawi, Feras Tarek Elgadi, Fahd Abdulla Algady Thaher, Awad Husein Shebl, Mohamed Ahmed Allam, Adel Mohamed Kehinde, Elija |
| Copyright Year | 2017 |
| Abstract | CONTEXT Lower urinary tract symptoms (LUTSs) in elderly males are usually related to benign prostatic hyperplasia (BPH) in the majority of cases. It is estimated that BPH affects half of men above the age of 50 years. Recently, a relationship between Vitamin D deficiency and LUTS in elderly males has been reported. AIMS The aim of this study was to analyze Vitamin D levels in males aged above 50 years presenting with LUTS. SETTINGS AND DESIGN This is a prospective case-control study. PATIENTS AND METHODS This was a case-control study in which males above 50 years of age who presented with LUTS (Group A) were compared with a control group (Group B) without LUTS. Both groups were investigated regarding Vitamin D level, prostate-specific antigen (PSA), International Prostatic Symptoms Score (IPSS), prostate size, flow rate, serum calcium levels, and abdominal ultrasonography. STATISTICAL ANALYSIS USED Statistical software package (SPSS Inc., Chicago, IL, USA) was used for the statistical analyses, performing t-test for quantitative data to compare between the two groups. Pearson's correlation coefficient "r" test was calculated between two quantitative, continuous variables in Group A. P <0.05 was considered statistically significant. RESULTS A total of 150 patients were studied. There were 70 and 80 patients in Groups A and B, respectively. The mean age of Group A patients was 60.32 ± 11.93 years versus 58.12 ± 10.55 years for Group B patients (P > 0.05). The mean value of Vitamin D level was 40.82 ± 29.46 nmol/L in Group A and 70.25 ± 22.42 nmol/L in Group B (P < 0.001). The mean value of prostate size was 50.12 ± 23.24 g in Group A and 30.68 ± 4.90 g in Group B (P < 0.001). The mean serum calcium level was 2.4 ± 0.14 mmol/L and 2.50 ± 0.15 mmol/L in Groups A and B, respectively (P < 0.001). The mean value of PSA in Group A was 2.24 ± 1.95 ng/ml versus 2.11 ± 0.45 ng/ml in Group B (P < 0.001). The mean value of IPSS in Group A was 13.38 ± 5.32 ml/s versus 3.41 ± 2.42 ml/s in Group B. The mean value of Q max in uroflowmetry in Group A was 11.5 ± 2 ml/s versus 15.4 ± 1 ml/s in Group B. CONCLUSIONS Men older than 50 years of age with LUTS have lower levels of Vitamin D compared to men without LUTS. |
| Starting Page | 170 |
| Ending Page | 173 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://vitamindwiki.com/tiki-download_wiki_attachment.php?attId=8141&download=y&page=Prostate+and+Urinary+systems+much+better+with+higher+vitamin+D+%E2%80%93+many+studies |
| PubMed reference number | 28479770v1 |
| Alternate Webpage(s) | https://doi.org/10.4103/0974-7796.204192 |
| DOI | 10.4103/0974-7796.204192 |
| Journal | Urology annals |
| Volume Number | 9 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Benign Prostatic Hyperplasia Coefficient Eighty International Prognostic Scoring System (IPSS) for Myelodysplastic Syndromes Lower Urinary Tract Symptoms Microgram per Liter Nanomole Patients Prostate Prostatic Neoplasms Serum Calcium Level Serum calcium measurement Urinary tract infection Vitamin D Deficiency millimole t test |
| Content Type | Text |
| Resource Type | Article |
