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Adrenal response to corticotropin during therapy with itraconazole.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Phillips, Philip Graybill, John Richard Fetchick, R. J. Dunn, Jeffrey F. |
| Copyright Year | 1987 |
| Abstract | Itraconazole is a triazole with a mechanism of action similar to that of ketoconazole. Endocrine side effects of ketoconazole, including impaired cortisol synthesis, have been well documented (A. Pont, J. R. Graybill, P. C. Craven, J. N. Galgiani, W. E. Dismukes, R. E. Reitz, and D. A. Stevens, Arch. Intern. Med. 144:2150-2153, 1984). We examined the adrenal response to corticotropin in 10 patients being treated with itraconazole. No impairment of cortisol synthesis could be demonstrated. |
| Starting Page | 22 |
| Ending Page | 28 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://aac.asm.org/content/31/4/647.full.pdf |
| PubMed reference number | 3038002v1 |
| Volume Number | 31 |
| Issue Number | 4 |
| Journal | Antimicrobial agents and chemotherapy |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adrenal Glands Hydrocortisone Itraconazole Ketoconazole Patients Triazoles cortisol biosynthetic process |
| Content Type | Text |
| Resource Type | Article |
